Activation of the hypoxia-inducible factor 1α promotes myogenesis through the noncanonical Wnt pathway, leading to hypertrophic myotubes.
Cirillo F, Resmini G, Ghiroldi A, Piccoli M, Bergante S, Tettamanti G, Anastasia L.
Cirillo F, et al. Among authors: ghiroldi a.
FASEB J. 2017 May;31(5):2146-2156. doi: 10.1096/fj.201600878R. Epub 2017 Feb 10.
FASEB J. 2017.
PMID: 28188178
Hypoxia has been recognized as a key factor to maintain stem cells in an undifferentiated state. ...Although preliminary, these findings may suggest new perspective for novel therapeutic targets in the treatment of several muscle diseases.-Cirillo, F., Resmini, G., Ghir …
Hypoxia has been recognized as a key factor to maintain stem cells in an undifferentiated state. ...Although preliminary, these findi …