Ghodge SV - Search Results

1

Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.

Chavarria-Smith J, Chiu CPC, Jackman JK, Yin J, Zhang J, Hackney JA, Lin WY, Tyagi T, Sun Y, Tao J, Dunlap D, Morton WD, Ghodge SV, Maun HR, Li H, Hernandez-Barry H, Loyet KM, Chen E, Liu J, Tam C, Yaspan BL, Cai H, Balazs M, Arron JR, Li J, Wittwer AJ, Pappu R, Austin CD, Lee WP, Lazarus RA, Sudhamsu J, Koerber JT, Yi T. Chavarria-Smith J, et al. Among authors: ghodge sv. Sci Transl Med. 2022 Dec 14;14(675):eabp9159. doi: 10.1126/scitranslmed.abp9159. Epub 2022 Dec 14. Sci Transl Med. 2022. PMID: 36516271

2

Exploring the Post-translational Enzymology of PaaA by mRNA Display.

Fleming SR, Himes PM, Ghodge SV, Goto Y, Suga H, Bowers AA. Fleming SR, et al. Among authors: ghodge sv. J Am Chem Soc. 2020 Mar 18;142(11):5024-5028. doi: 10.1021/jacs.0c01576. Epub 2020 Mar 6. J Am Chem Soc. 2020. PMID: 32109054 Free PMC article.

3

Mapping the sites of the lipoprotein lipase (LPL)-angiopoietin-like protein 4 (ANGPTL4) interaction provides mechanistic insight into LPL inhibition.

Gutgsell AR, Ghodge SV, Bowers AA, Neher SB. Gutgsell AR, et al. Among authors: ghodge sv. J Biol Chem. 2019 Feb 22;294(8):2678-2689. doi: 10.1074/jbc.RA118.005932. Epub 2018 Dec 27. J Biol Chem. 2019. PMID: 30591589 Free PMC article.

4

Structure, Mechanism, and Substrate Profiles of the Trinuclear Metallophosphatases from the Amidohydrolase Superfamily.

Ghodge SV, Raushel FM. Ghodge SV, et al. Methods Enzymol. 2018;607:187-216. doi: 10.1016/bs.mie.2018.04.019. Epub 2018 Jul 19. Methods Enzymol. 2018. PMID: 30149858 Review.

5

P450-Mediated Non-natural Cyclopropanation of Dehydroalanine-Containing Thiopeptides.

Gober JG, Ghodge SV, Bogart JW, Wever WJ, Watkins RR, Brustad EM, Bowers AA. Gober JG, et al. Among authors: ghodge sv. ACS Chem Biol. 2017 Jul 21;12(7):1726-1731. doi: 10.1021/acschembio.7b00358. Epub 2017 Jun 1. ACS Chem Biol. 2017. PMID: 28535034

6

Post-translational Claisen Condensation and Decarboxylation en Route to the Bicyclic Core of Pantocin A.

Ghodge SV, Biernat KA, Bassett SJ, Redinbo MR, Bowers AA. Ghodge SV, et al. J Am Chem Soc. 2016 May 4;138(17):5487-90. doi: 10.1021/jacs.5b13529. Epub 2016 Apr 22. J Am Chem Soc. 2016. PMID: 27088303 Free PMC article.

7

Discovery of a Previously Unrecognized Ribonuclease from Escherichia coli That Hydrolyzes 5'-Phosphorylated Fragments of RNA.

Ghodge SV, Raushel FM. Ghodge SV, et al. Biochemistry. 2015 May 12;54(18):2911-8. doi: 10.1021/acs.biochem.5b00192. Epub 2015 Apr 28. Biochemistry. 2015. PMID: 25871919

8

Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily.

Cummings JA, Vetting M, Ghodge SV, Xu C, Hillerich B, Seidel RD, Almo SC, Raushel FM. Cummings JA, et al. Among authors: ghodge sv. Biochemistry. 2014 Jan 28;53(3):591-600. doi: 10.1021/bi401640r. Epub 2014 Jan 13. Biochemistry. 2014. PMID: 24401123 Free PMC article.

9

Discovery of a cyclic phosphodiesterase that catalyzes the sequential hydrolysis of both ester bonds to phosphorus.

Ghodge SV, Cummings JA, Williams HJ, Raushel FM. Ghodge SV, et al. J Am Chem Soc. 2013 Nov 6;135(44):16360-3. doi: 10.1021/ja409376k. Epub 2013 Oct 24. J Am Chem Soc. 2013. PMID: 24147537 Free PMC article.

10

Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins.

Ghodge SV, Fedorov AA, Fedorov EV, Hillerich B, Seidel R, Almo SC, Raushel FM. Ghodge SV, et al. Biochemistry. 2013 Feb 12;52(6):1101-12. doi: 10.1021/bi301496p. Epub 2013 Jan 30. Biochemistry. 2013. PMID: 23327428 Free PMC article.

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