Giachetti A - Search Results

1

Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.

Terzuoli E, Donnini S, Finetti F, Nesi G, Villari D, Hanaka H, Radmark O, Giachetti A, Ziche M. Terzuoli E, et al. Among authors: giachetti a. Oncotarget. 2016 Jul 12;7(28):44350-44364. doi: 10.18632/oncotarget.10051. Oncotarget. 2016. PMID: 27322147 Free PMC article.

2

EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.

Donnini S, Finetti F, Terzuoli E, Giachetti A, Iñiguez MA, Hanaka H, Fresno M, Rådmark O, Ziche M. Donnini S, et al. Among authors: giachetti a. Oncogene. 2012 Jul 19;31(29):3457-66. doi: 10.1038/onc.2011.503. Epub 2011 Nov 14. Oncogene. 2012. PMID: 22081067

3

Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.

Terzuoli E, Donnini S, Giachetti A, Iñiguez MA, Fresno M, Melillo G, Ziche M. Terzuoli E, et al. Among authors: giachetti a. Clin Cancer Res. 2010 Aug 15;16(16):4207-16. doi: 10.1158/1078-0432.CCR-10-0156. Epub 2010 Aug 3. Clin Cancer Res. 2010. PMID: 20682710

4

Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis.

Finetti F, Terzuoli E, Bocci E, Coletta I, Polenzani L, Mangano G, Alisi MA, Cazzolla N, Giachetti A, Ziche M, Donnini S. Finetti F, et al. Among authors: giachetti a. PLoS One. 2012;7(7):e40576. doi: 10.1371/journal.pone.0040576. Epub 2012 Jul 18. PLoS One. 2012. PMID: 22815767 Free PMC article.

5

mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.

Finetti F, Terzuoli E, Giachetti A, Santi R, Villari D, Hanaka H, Radmark O, Ziche M, Donnini S. Finetti F, et al. Among authors: giachetti a. Endocr Relat Cancer. 2015 Aug;22(4):665-78. doi: 10.1530/ERC-15-0277. Epub 2015 Jun 25. Endocr Relat Cancer. 2015. PMID: 26113609 Free PMC article.

6

Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells.

Terzuoli E, Nannelli G, Frosini M, Giachetti A, Ziche M, Donnini S. Terzuoli E, et al. Among authors: giachetti a. Oncotarget. 2017 Aug 24;8(47):83207-83224. doi: 10.18632/oncotarget.20544. eCollection 2017 Oct 10. Oncotarget. 2017. PMID: 29137335 Free PMC article.

7

PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells.

Bazzani L, Donnini S, Giachetti A, Christofori G, Ziche M. Bazzani L, et al. Among authors: giachetti a. Oncotarget. 2018 Feb 15;9(19):14939-14958. doi: 10.18632/oncotarget.24499. eCollection 2018 Mar 13. Oncotarget. 2018. PMID: 29599917 Free PMC article.

8

Angiosuppressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin.

Morbidelli L, Donnini S, Chillemi F, Giachetti A, Ziche M. Morbidelli L, et al. Among authors: giachetti a. Clin Cancer Res. 2003 Nov 1;9(14):5358-69. Clin Cancer Res. 2003. PMID: 14614021

9

Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1.

Finetti F, Solito R, Morbidelli L, Giachetti A, Ziche M, Donnini S. Finetti F, et al. Among authors: giachetti a. J Biol Chem. 2008 Jan 25;283(4):2139-46. doi: 10.1074/jbc.M703090200. Epub 2007 Nov 26. J Biol Chem. 2008. PMID: 18042549 Free article.

10

Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway.

Finetti F, Donnini S, Giachetti A, Morbidelli L, Ziche M. Finetti F, et al. Among authors: giachetti a. Circ Res. 2009 Sep 25;105(7):657-66. doi: 10.1161/CIRCRESAHA.109.203760. Epub 2009 Aug 27. Circ Res. 2009. PMID: 19713533

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