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Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.
Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, Alpini G. Zhou T, et al. Among authors: giang tk. Lab Invest. 2018 Nov;98(11):1449-1464. doi: 10.1038/s41374-018-0093-9. Epub 2018 Jul 5. Lab Invest. 2018. PMID: 29977037 Free PMC article.
The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.
Wu N, Meng F, Zhou T, Venter J, Giang TK, Kyritsi K, Wu C, Alvaro D, Onori P, Mancinelli R, Gaudio E, Francis H, Alpini G, Glaser S, Franchitto A. Wu N, et al. Among authors: giang tk. Am J Pathol. 2018 Oct;188(10):2264-2280. doi: 10.1016/j.ajpath.2018.06.015. Epub 2018 Jul 21. Am J Pathol. 2018. PMID: 30036520 Free PMC article.
Mechanisms of cholangiocyte responses to injury.
Sato K, Meng F, Giang T, Glaser S, Alpini G. Sato K, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1262-1269. doi: 10.1016/j.bbadis.2017.06.017. Epub 2017 Jun 23. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 28648950 Free PMC article. Review.
Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.
McMillin M, DeMorrow S, Glaser S, Venter J, Kyritsi K, Zhou T, Grant S, Giang T, Greene JF Jr, Wu N, Jefferson B, Meng F, Alpini G. McMillin M, et al. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G410-G418. doi: 10.1152/ajpgi.00421.2016. Epub 2017 Jul 27. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28751425 Free PMC article.
Knockout of the Tachykinin Receptor 1 in the Mdr2-/- (Abcb4-/-) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis.
Ceci L, Francis H, Zhou T, Giang T, Yang Z, Meng F, Wu N, Kennedy L, Kyritsi K, Meadows V, Wu C, Liangpunsakul S, Franchitto A, Sybenga A, Ekser B, Mancinelli R, Onori P, Gaudio E, Glaser S, Alpini G. Ceci L, et al. Am J Pathol. 2020 Nov;190(11):2251-2266. doi: 10.1016/j.ajpath.2020.07.007. Epub 2020 Jul 23. Am J Pathol. 2020. PMID: 32712019 Free PMC article.
Associations of the microbiome and esophageal disease.
Okereke I, Hamilton C, Wenholz A, Jala V, Giang T, Reynolds S, Miller A, Pyles R. Okereke I, et al. J Thorac Dis. 2019 Aug;11(Suppl 12):S1588-S1593. doi: 10.21037/jtd.2019.05.82. J Thorac Dis. 2019. PMID: 31489225 Free PMC article. Review.
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