Gierthy JF - Search Results

1

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase.

Spink DC, Hayes CL, Young NR, Christou M, Sutter TR, Jefcoate CR, Gierthy JF. Spink DC, et al. Among authors: gierthy jf. J Steroid Biochem Mol Biol. 1994 Dec;51(5-6):251-8. doi: 10.1016/0960-0760(94)90037-x. J Steroid Biochem Mol Biol. 1994. PMID: 7826886

2

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA.

Spink DC, Eugster HP, Lincoln DW 2nd, Schuetz JD, Schuetz EG, Johnson JA, Kaminsky LS, Gierthy JF. Spink DC, et al. Among authors: gierthy jf. Arch Biochem Biophys. 1992 Mar;293(2):342-8. doi: 10.1016/0003-9861(92)90404-k. Arch Biochem Biophys. 1992. PMID: 1536570

3

2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells.

Spink DC, Lincoln DW 2nd, Dickerman HW, Gierthy JF. Spink DC, et al. Among authors: gierthy jf. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6917-21. doi: 10.1073/pnas.87.17.6917. Proc Natl Acad Sci U S A. 1990. PMID: 2395886 Free PMC article.

4

Stimulation of 17 beta-estradiol metabolism in MCF-7 cells by bromochloro- and chloromethyl-substituted dibenzo-p-dioxins and dibenzofurans: correlations with antiestrogenic activity.

Spink DC, Johnson JA, Connor SP, Aldous KM, Gierthy JF. Spink DC, et al. Among authors: gierthy jf. J Toxicol Environ Health. 1994 Apr;41(4):451-66. doi: 10.1080/15287399409531856. J Toxicol Environ Health. 1994. PMID: 8145285

5

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 12-O-tetradecanoylphorbol-13-acetate and 17 beta-estradiol on estrogen receptor regulation in MCF-7 human breast cancer cells.

Gierthy JF, Spink BC, Figge HL, Pentecost BT, Spink DC. Gierthy JF, et al. J Cell Biochem. 1996 Feb;60(2):173-84. doi: 10.1002/(sici)1097-4644(19960201)60:2<173::aid-jcb2>3.0.co;2-u. J Cell Biochem. 1996. PMID: 8655628

6

Induction of cytochrome P450 1B1 and catechol estrogen metabolism in ACHN human renal adenocarcinoma cells.

Spink DC, Spink BC, Cao JQ, Gierthy JF, Hayes CL, Li Y, Sutter TR. Spink DC, et al. Among authors: gierthy jf. J Steroid Biochem Mol Biol. 1997 Jun;62(2-3):223-32. doi: 10.1016/s0960-0760(97)00024-1. J Steroid Biochem Mol Biol. 1997. PMID: 9393958 Free article.

7

12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells.

Spink BC, Fasco MJ, Gierthy JF, Spink DC. Spink BC, et al. Among authors: gierthy jf. J Cell Biochem. 1998 Sep 1;70(3):289-96. J Cell Biochem. 1998. PMID: 9706865

8

NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1.

Spink DC, Spink BC, Zhuo X, Hussain MM, Gierthy JF, Ding X. Spink DC, et al. Among authors: gierthy jf. J Steroid Biochem Mol Biol. 2000 Sep;74(1-2):11-8. doi: 10.1016/s0960-0760(00)00083-2. J Steroid Biochem Mol Biol. 2000. PMID: 11074351

9

Inhibition of MCF-7 breast cancer cell proliferation by MCF-10A breast epithelial cells in coculture.

Spink BC, Cole RW, Katz BH, Gierthy JF, Bradley LM, Spink DC. Spink BC, et al. Among authors: gierthy jf. Cell Biol Int. 2006 Mar;30(3):227-38. doi: 10.1016/j.cellbi.2005.11.006. Epub 2006 Jan 19. Cell Biol Int. 2006. PMID: 16427788

10

Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells.

Christou M, Savas U, Spink DC, Gierthy JF, Jefcoate CR. Christou M, et al. Among authors: gierthy jf. Carcinogenesis. 1994 Apr;15(4):725-32. doi: 10.1093/carcin/15.4.725. Carcinogenesis. 1994. PMID: 8149487

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