Gillies JK - Search Results

1

Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity.

Lam AJ, Lin DTS, Gillies JK, Uday P, Pesenacker AM, Kobor MS, Levings MK. Lam AJ, et al. Among authors: gillies jk. Cell Rep. 2021 Aug 3;36(5):109494. doi: 10.1016/j.celrep.2021.109494. Cell Rep. 2021. PMID: 34348163 Free article.

2

Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.

McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK. McMurchy AN, et al. J Allergy Clin Immunol. 2010 Dec;126(6):1242-51. doi: 10.1016/j.jaci.2010.09.001. Epub 2010 Oct 30. J Allergy Clin Immunol. 2010. PMID: 21036387

3

A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells.

McMurchy AN, Gillies J, Gizzi MC, Riba M, Garcia-Manteiga JM, Cittaro D, Lazarevic D, Di Nunzio S, Piras IS, Bulfone A, Roncarolo MG, Stupka E, Bacchetta R, Levings MK. McMurchy AN, et al. Blood. 2013 Feb 21;121(8):1265-75. doi: 10.1182/blood-2012-05-431023. Epub 2012 Nov 20. Blood. 2013. PMID: 23169781 Free article.

4

A Regulatory T-Cell Gene Signature Is a Specific and Sensitive Biomarker to Identify Children With New-Onset Type 1 Diabetes.

Pesenacker AM, Wang AY, Singh A, Gillies J, Kim Y, Piccirillo CA, Nguyen D, Haining WN, Tebbutt SJ, Panagiotopoulos C, Levings MK. Pesenacker AM, et al. Diabetes. 2016 Apr;65(4):1031-9. doi: 10.2337/db15-0572. Epub 2016 Jan 19. Diabetes. 2016. PMID: 26786322

5

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression.

Patterson SJ, Pesenacker AM, Wang AY, Gillies J, Mojibian M, Morishita K, Tan R, Kieffer TJ, Verchere CB, Panagiotopoulos C, Levings MK. Patterson SJ, et al. J Clin Invest. 2016 Mar 1;126(3):1039-51. doi: 10.1172/JCI83987. Epub 2016 Feb 8. J Clin Invest. 2016. PMID: 26854929 Free PMC article.

6

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.

MacDonald KG, Hoeppli RE, Huang Q, Gillies J, Luciani DS, Orban PC, Broady R, Levings MK. MacDonald KG, et al. J Clin Invest. 2016 Apr 1;126(4):1413-24. doi: 10.1172/JCI82771. Epub 2016 Mar 21. J Clin Invest. 2016. PMID: 26999600 Free PMC article.

7

Circulating gluten-specific FOXP3⁺CD39⁺ regulatory T cells have impaired suppressive function in patients with celiac disease.

Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid HH, Petersen J, Rossjohn J, Anderson RP, Zaunders JJ, Tye-Din JA, Kelleher AD. Cook L, et al. Among authors: gillies jk. J Allergy Clin Immunol. 2017 Dec;140(6):1592-1603.e8. doi: 10.1016/j.jaci.2017.02.015. Epub 2017 Mar 8. J Allergy Clin Immunol. 2017. PMID: 28283419 Free article.

8

Tailoring the homing capacity of human Tregs for directed migration to sites of Th1-inflammation or intestinal regions.

Hoeppli RE, MacDonald KN, Leclair P, Fung VCW, Mojibian M, Gillies J, Rahavi SMR, Campbell AIM, Gandhi SK, Pesenacker AM, Reid G, Lim CJ, Levings MK. Hoeppli RE, et al. Am J Transplant. 2019 Jan;19(1):62-76. doi: 10.1111/ajt.14936. Epub 2018 Jun 13. Am J Transplant. 2019. PMID: 29766641 Free article.

9

Treg gene signatures predict and measure type 1 diabetes trajectory.

Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK. Pesenacker AM, et al. JCI Insight. 2019 Mar 21;4(6):e123879. doi: 10.1172/jci.insight.123879. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30730852 Free PMC article. Clinical Trial.

10

Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells.

Dawson NA, Lamarche C, Hoeppli RE, Bergqvist P, Fung VC, McIver E, Huang Q, Gillies J, Speck M, Orban PC, Bush JW, Mojibian M, Levings MK. Dawson NA, et al. JCI Insight. 2019 Mar 21;4(6):e123672. doi: 10.1172/jci.insight.123672. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30753169 Free PMC article.

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