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Mre11-Rad50 oligomerization promotes DNA double-strand break repair.
Kissling VM, Reginato G, Bianco E, Kasaciunaite K, Tilma J, Cereghetti G, Schindler N, Lee SS, Guérois R, Luke B, Seidel R, Cejka P, Peter M. Kissling VM, et al. Among authors: reginato g. Nat Commun. 2022 May 2;13(1):2374. doi: 10.1038/s41467-022-29841-0. Nat Commun. 2022. PMID: 35501303 Free PMC article.
Xrs2/NBS1 promote end-bridging activity of the MRE11-RAD50 complex.
Möller C, Sharma R, Öz R, Reginato G, Cannavo E, Ceppi I, Sriram KK, Cejka P, Westerlund F. Möller C, et al. Among authors: reginato g. Biochem Biophys Res Commun. 2024 Feb 5;695:149464. doi: 10.1016/j.bbrc.2023.149464. Epub 2023 Dec 30. Biochem Biophys Res Commun. 2024. PMID: 38217957 Free article.
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A. Casini A, et al. Among authors: reginato g. Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29. Nat Biotechnol. 2018. PMID: 29431739 Free PMC article.
13 results