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Reversal of Defective Mitochondrial Biogenesis in Limb-Girdle Muscular Dystrophy 2D by Independent Modulation of Histone and PGC-1α Acetylation.
Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C. Pambianco S, et al. Among authors: giovarelli m. Cell Rep. 2016 Dec 13;17(11):3010-3023. doi: 10.1016/j.celrep.2016.11.044. Cell Rep. 2016. PMID: 27974213 Free article.
Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition.
Perrotta C, Cervia D, Di Renzo I, Moscheni C, Bassi MT, Campana L, Martelli C, Catalani E, Giovarelli M, Zecchini S, Coazzoli M, Capobianco A, Ottobrini L, Lucignani G, Rosa P, Rovere-Querini P, De Palma C, Clementi E. Perrotta C, et al. Among authors: giovarelli m. Front Immunol. 2018 May 29;9:1186. doi: 10.3389/fimmu.2018.01186. eCollection 2018. Front Immunol. 2018. PMID: 29896202 Free PMC article.
Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells.
Zecchini S, Proietti Serafini F, Catalani E, Giovarelli M, Coazzoli M, Di Renzo I, De Palma C, Perrotta C, Clementi E, Buonanno F, Ortenzi C, Marcantoni E, Taddei AR, Picchietti S, Fausto AM, Cervia D. Zecchini S, et al. Among authors: giovarelli m. Cell Death Dis. 2018 Dec 19;10(1):10. doi: 10.1038/s41419-018-1254-x. Cell Death Dis. 2018. PMID: 30584259 Free PMC article.
The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli.
Pedrotti S, Caccia R, Neguembor MV, Garcia-Manteiga JM, Ferri G, de Palma C, Canu T, Giovarelli M, Marra P, Fiocchi A, Molineris I, Raso M, Sanvito F, Doglioni C, Esposito A, Clementi E, Gabellini D. Pedrotti S, et al. Among authors: giovarelli m. Sci Adv. 2019 Apr 17;5(4):eaav1472. doi: 10.1126/sciadv.aav1472. eCollection 2019 Apr. Sci Adv. 2019. PMID: 31001581 Free PMC article.
The Natural Compound Climacostol as a Prodrug Strategy Based on pH Activation for Efficient Delivery of Cytotoxic Small Agents.
Catalani E, Buonanno F, Lupidi G, Bongiorni S, Belardi R, Zecchini S, Giovarelli M, Coazzoli M, De Palma C, Perrotta C, Clementi E, Prantera G, Marcantoni E, Ortenzi C, Fausto AM, Picchietti S, Cervia D. Catalani E, et al. Among authors: giovarelli m. Front Chem. 2019 Jun 28;7:463. doi: 10.3389/fchem.2019.00463. eCollection 2019. Front Chem. 2019. PMID: 31316972 Free PMC article.
XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death.
Muñoz D, Brucoli M, Zecchini S, Sandoval-Hernandez A, Arboleda G, Lopez-Vallejo F, Delgado W, Giovarelli M, Coazzoli M, Catalani E, De Palma C, Perrotta C, Cuca L, Clementi E, Cervia D. Muñoz D, et al. Among authors: giovarelli m. Cancers (Basel). 2019 Sep 9;11(9):1336. doi: 10.3390/cancers11091336. Cancers (Basel). 2019. PMID: 31505859 Free PMC article.
Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle.
Giovarelli M, Zecchini S, Martini E, Garrè M, Barozzi S, Ripolone M, Napoli L, Coazzoli M, Vantaggiato C, Roux-Biejat P, Cervia D, Moscheni C, Perrotta C, Parazzoli D, Clementi E, De Palma C. Giovarelli M, et al. Cell Death Differ. 2020 Aug;27(8):2383-2401. doi: 10.1038/s41418-020-0510-7. Epub 2020 Feb 10. Cell Death Differ. 2020. PMID: 32042098 Free PMC article.
191 results