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Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response.
Gsottberger F, Meier C, Ammon A, Parker S, Wendland K, George R, Petkovic S, Mellenthin L, Emmerich C, Lutzny-Geier G, Metzler M, Mackensen A, Chandramohan V, Müller F. Gsottberger F, et al. Among authors: lutzny geier g. Cell Death Dis. 2023 Aug 26;14(8):561. doi: 10.1038/s41419-023-06055-w. Cell Death Dis. 2023. PMID: 37626037 Free PMC article.
Fully Human Anti-CD19 CAR T Cells Derived from Systemic Lupus Erythematosus Patients Exhibit Cytotoxicity with Reduced Inflammatory Cytokine Production.
Dingfelder J, Aigner M, Taubmann J, Minopoulou I, Park S, Kaplan CD, Cheng JK, Van Blarcom T, Schett G, Mackensen A, Lutzny-Geier G. Dingfelder J, et al. Among authors: lutzny geier g. Transplant Cell Ther. 2024 Mar 26:S2666-6367(24)00297-5. doi: 10.1016/j.jtct.2024.03.023. Online ahead of print. Transplant Cell Ther. 2024. PMID: 38548226 Free article.
Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia.
Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny-Geier G, Klein-Hitpass L, Williamson JC, Lehner PJ, Dürig J, Möllmann M, Rásó-Barnett L, Hughes K, Santoro A, Méndez-Ferrer S, Oostendorp RAJ, Zimber-Strobl U, Peschel C, Hodson DJ, Schmidt-Supprian M, Ringshausen I. Mangolini M, et al. Among authors: lutzny geier g. Nat Commun. 2018 Sep 21;9(1):3839. doi: 10.1038/s41467-018-06069-5. Nat Commun. 2018. PMID: 30242258 Free PMC article.
Influence of DM-sensitivity on immunogenicity of MHC class II restricted antigens.
Bernhardt AL, Zeun J, Marecek M, Reimann H, Kretschmann S, Bausenwein J, van der Meijden ED, Karg MM, Haug T, Meintker L, Lutzny-Geier G, Mackensen A, Kremer AN. Bernhardt AL, et al. Among authors: lutzny geier g. J Immunother Cancer. 2021 Jul;9(7):e002401. doi: 10.1136/jitc-2021-002401. J Immunother Cancer. 2021. PMID: 34266882 Free PMC article.
Successful treatment of COVID-19 infection with convalescent plasma in B-cell-depleted patients may promote cellular immunity.
Kremer AE, Kremer AN, Willam C, Völkl S, Verhagen J, Achenbach S, van der Meijden ED, Lang V, Aigner M, Maier C, Tenbusch M, Korn K, Lutzny-Geier G, Spoerl S, Strauß R, Vetter M, Überla K, Neurath MF, Mackensen A, Schiffer M, Hackstein H. Kremer AE, et al. Among authors: lutzny geier g. Eur J Immunol. 2021 Oct;51(10):2478-2484. doi: 10.1002/eji.202149277. Epub 2021 Sep 3. Eur J Immunol. 2021. PMID: 34350584 Free PMC article.
Upregulation of CCR4 in activated CD8+ T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection.
Spoerl S, Kremer AN, Aigner M, Eisenhauer N, Koch P, Meretuk L, Löffler P, Tenbusch M, Maier C, Überla K, Heinzerling L, Frey B, Lutzny-Geier G, Winkler TH, Krönke G, Vetter M, Bruns H, Neurath MF, Mackensen A, Kremer AE, Völkl S. Spoerl S, et al. Among authors: lutzny geier g. Eur J Immunol. 2021 Jun;51(6):1436-1448. doi: 10.1002/eji.202049135. Epub 2021 Apr 19. Eur J Immunol. 2021. PMID: 33784417 Free PMC article. Clinical Trial.