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PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination.
Gharibani P, Abramson E, Shanmukha S, Smith MD, Godfrey WH, Lee JJ, Hu J, Baydyuk M, Dorion MF, Deng X, Guo Y, Hwang S, Huang JK, Calabresi PA, Kornberg MD, Kim PM. Gharibani P, et al. Among authors: godfrey wh. bioRxiv [Preprint]. 2023 Aug 29:2023.08.28.555084. doi: 10.1101/2023.08.28.555084. bioRxiv. 2023. PMID: 37693473 Free PMC article. Preprint.
Tumor-associated myeloid cells provide critical support for T-ALL.
Lyu A, Triplett TA, Nam SH, Hu Z, Arasappan D, Godfrey WH, Ames RY, Sarang A, Selden HJ, Lee CH, Georgiou G, Horton TM, Ehrlich LIR. Lyu A, et al. Among authors: godfrey wh. Blood. 2020 Oct 15;136(16):1837-1850. doi: 10.1182/blood.2020007145. Blood. 2020. PMID: 32845007 Free article.