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Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.
Suzuki K, Yu C, Qu J, Li M, Yao X, Yuan T, Goebl A, Tang S, Ren R, Aizawa E, Zhang F, Xu X, Soligalla RD, Chen F, Kim J, Kim NY, Liao HK, Benner C, Esteban CR, Jin Y, Liu GH, Li Y, Izpisua Belmonte JC. Suzuki K, et al. Among authors: goebl a. Cell Stem Cell. 2014 Jul 3;15(1):31-6. doi: 10.1016/j.stem.2014.06.016. Cell Stem Cell. 2014. PMID: 24996168 Free PMC article.
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.
Liu GH, Suzuki K, Qu J, Sancho-Martinez I, Yi F, Li M, Kumar S, Nivet E, Kim J, Soligalla RD, Dubova I, Goebl A, Plongthongkum N, Fung HL, Zhang K, Loring JF, Laurent LC, Izpisua Belmonte JC. Liu GH, et al. Among authors: goebl a. Cell Stem Cell. 2011 Jun 3;8(6):688-94. doi: 10.1016/j.stem.2011.04.019. Epub 2011 May 19. Cell Stem Cell. 2011. PMID: 21596650 Free PMC article.
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.
Liu GH, Qu J, Suzuki K, Nivet E, Li M, Montserrat N, Yi F, Xu X, Ruiz S, Zhang W, Wagner U, Kim A, Ren B, Li Y, Goebl A, Kim J, Soligalla RD, Dubova I, Thompson J, Yates J 3rd, Esteban CR, Sancho-Martinez I, Izpisua Belmonte JC. Liu GH, et al. Among authors: goebl a. Nature. 2012 Nov 22;491(7425):603-7. doi: 10.1038/nature11557. Epub 2012 Oct 17. Nature. 2012. PMID: 23075850 Free PMC article.
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.
Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, Del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Belmonte JCI. Liu GH, et al. Among authors: goebl a. Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330. Nat Commun. 2014. PMID: 24999918 Free PMC article.
Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. Zhang W, et al. Among authors: goebl a. Science. 2015 Jun 5;348(6239):1160-3. doi: 10.1126/science.aaa1356. Epub 2015 Apr 30. Science. 2015. PMID: 25931448 Free PMC article.
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Among authors: goebl a. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
Complete mitochondrial genomes provide current refined phylogenomic hypotheses for relationships among ten Hirundo species.
Carter JK, Innes P, Goebl AM, Johnson B, Gebert M, Attia Z, Gabani Z, Li R, Melie T, Dart C, Mares A, Greidanus C, Paterson J, Wall B, Cortese G, Thirouin K, Glime G, Rutten J, Poyd C, Post E, Wall B, Elhadi AA, Feldmann K, Danz A, Blanchard T, Amato S, Reinert S, Pogoda CS, Scordato ESC, Hund AK, Safran RJ, Kane NC. Carter JK, et al. Among authors: goebl am. Mitochondrial DNA B Resour. 2020 Jul 20;5(3):2881-2885. doi: 10.1080/23802359.2020.1790999. Mitochondrial DNA B Resour. 2020. PMID: 33457987 Free PMC article.
12 results