Goldfarb D - Search Results

1

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor.

Tamir TY, Bowman BM, Agajanian MJ, Goldfarb D, Schrank TP, Stohrer T, Hale AE, Siesser PF, Weir SJ, Murphy RM, LaPak KM, Weissman BE, Moorman NJ, Major MB. Tamir TY, et al. Among authors: goldfarb d. J Cell Sci. 2020 Jul 15;133(14):jcs241356. doi: 10.1242/jcs.241356. J Cell Sci. 2020. PMID: 32546533 Free PMC article.

2

FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility.

Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB. Siesser PF, et al. Among authors: goldfarb d. Sci Signal. 2012 Sep 4;5(240):ra64. doi: 10.1126/scisignal.2002871. Sci Signal. 2012. PMID: 22949735 Free PMC article.

3

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.

Hast BE, Goldfarb D, Mulvaney KM, Hast MA, Siesser PF, Yan F, Hayes DN, Major MB. Hast BE, et al. Among authors: goldfarb d. Cancer Res. 2013 Apr 1;73(7):2199-210. doi: 10.1158/0008-5472.CAN-12-4400. Epub 2013 Feb 4. Cancer Res. 2013. PMID: 23382044 Free PMC article.

4

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.

Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB. Hast BE, et al. Among authors: goldfarb d. Cancer Res. 2014 Feb 1;74(3):808-17. doi: 10.1158/0008-5472.CAN-13-1655. Epub 2013 Dec 9. Cancer Res. 2014. PMID: 24322982 Free PMC article.

5

SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.

Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y. Wei D, et al. Among authors: goldfarb d. Mol Cancer Res. 2014 Nov;12(11):1574-85. doi: 10.1158/1541-7786.MCR-14-0005. Epub 2014 Jul 9. Mol Cancer Res. 2014. PMID: 25009291 Free PMC article.

6

Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data.

Goldfarb D, Hast BE, Wang W, Major MB. Goldfarb D, et al. J Proteome Res. 2014 Dec 5;13(12):5944-55. doi: 10.1021/pr5008416. Epub 2014 Oct 20. J Proteome Res. 2014. PMID: 25300367 Free PMC article.

7

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

Kim TY, Siesser PF, Rossman KL, Goldfarb D, Mackinnon K, Yan F, Yi X, MacCoss MJ, Moon RT, Der CJ, Major MB. Kim TY, et al. Among authors: goldfarb d. Mol Cell Biol. 2015 Jan;35(1):167-81. doi: 10.1128/MCB.00857-14. Epub 2014 Oct 20. Mol Cell Biol. 2015. PMID: 25332235 Free PMC article.

8

FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.

Walker MP, Stopford CM, Cederlund M, Fang F, Jahn C, Rabinowitz AD, Goldfarb D, Graham DM, Yan F, Deal AM, Fedoriw Y, Richards KL, Davis IJ, Weidinger G, Damania B, Major MB. Walker MP, et al. Among authors: goldfarb d. Sci Signal. 2015 Feb 3;8(362):ra12. doi: 10.1126/scisignal.2005654. Sci Signal. 2015. PMID: 25650440 Free PMC article.

9

MSAcquisitionSimulator: data-dependent acquisition simulator for LC-MS shotgun proteomics.

Goldfarb D, Wang W, Major MB. Goldfarb D, et al. Bioinformatics. 2016 Apr 15;32(8):1269-71. doi: 10.1093/bioinformatics/btv745. Epub 2015 Dec 17. Bioinformatics. 2016. PMID: 26685308 Free PMC article.

10

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

Gao Y, Mutter-Rottmayer E, Greenwalt AM, Goldfarb D, Yan F, Yang Y, Martinez-Chacin RC, Pearce KH, Tateishi S, Major MB, Vaziri C. Gao Y, et al. Among authors: goldfarb d. Nat Commun. 2016 Jul 5;7:12105. doi: 10.1038/ncomms12105. Nat Commun. 2016. PMID: 27377895 Free PMC article.

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