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Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.
Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H. Joseph A, et al. Among authors: goldstein h. J Virol. 2008 Mar;82(6):3078-89. doi: 10.1128/JVI.01812-07. Epub 2008 Jan 9. J Virol. 2008. PMID: 18184707 Free PMC article.
Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice.
Osiecki K, Xie L, Zheng JH, Squires R, Pettoello-Mantovani M, Goldstein H. Osiecki K, et al. Among authors: goldstein h. AIDS Res Hum Retroviruses. 2005 Feb;21(2):125-39. doi: 10.1089/aid.2005.21.125. AIDS Res Hum Retroviruses. 2005. PMID: 15725751
CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate.
Sun J, Soos T, Kewalramani VN, Osiecki K, Zheng JH, Falkin L, Santambrogio L, Littman DR, Goldstein H. Sun J, et al. Among authors: goldstein h. J Virol. 2006 Feb;80(4):1850-62. doi: 10.1128/JVI.80.4.1850-1862.2006. J Virol. 2006. PMID: 16439541 Free PMC article.
Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope.
Schaubert KL, Price DA, Frahm N, Li J, Ng HL, Joseph A, Paul E, Majumder B, Ayyavoo V, Gostick E, Adams S, Marincola FM, Sewell AK, Altfeld M, Brenchley JM, Douek DC, Yang OO, Brander C, Goldstein H, Kan-Mitchell J. Schaubert KL, et al. Among authors: goldstein h. J Immunol. 2007 Jun 15;178(12):7756-66. doi: 10.4049/jimmunol.178.12.7756. J Immunol. 2007. PMID: 17548613 Free PMC article.
Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysaccharides.
Sun J, Zheng JH, Zhao M, Lee S, Goldstein H. Sun J, et al. Among authors: goldstein h. J Virol. 2008 Jun;82(11):5562-72. doi: 10.1128/JVI.02618-07. Epub 2008 Mar 19. J Virol. 2008. PMID: 18353948 Free PMC article.
765 results