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The HIV antiretroviral drug efavirenz has LSD-like properties.
Gatch MB, Kozlenkov A, Huang RQ, Yang W, Nguyen JD, González-Maeso J, Rice KC, France CP, Dillon GH, Forster MJ, Schetz JA. Gatch MB, et al. Neuropsychopharmacology. 2013 Nov;38(12):2373-84. doi: 10.1038/npp.2013.135. Epub 2013 May 24. Neuropsychopharmacology. 2013. PMID: 23702798 Free PMC article.
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.
Kurita M, Holloway T, García-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umali A, Callado LF, Gallitano AL, Neve RL, Shen L, Buxbaum JD, Han MH, Nestler EJ, Meana JJ, Russo SJ, González-Maeso J. Kurita M, et al. Nat Neurosci. 2012 Sep;15(9):1245-54. doi: 10.1038/nn.3181. Epub 2012 Aug 5. Nat Neurosci. 2012. PMID: 22864611 Free PMC article.
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, Robakis NK, Logothetis DE, Meana JJ, González-Maeso J. Moreno JL, et al. Sci Signal. 2016 Jan 12;9(410):ra5. doi: 10.1126/scisignal.aab0467. Sci Signal. 2016. PMID: 26758213 Free PMC article.
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins.
García-Bea A, Miranda-Azpiazu P, Muguruza C, Marmolejo-Martinez-Artesero S, Diez-Alarcia R, Gabilondo AM, Callado LF, Morentin B, González-Maeso J, Meana JJ. García-Bea A, et al. Eur Neuropsychopharmacol. 2019 Dec;29(12):1453-1463. doi: 10.1016/j.euroneuro.2019.10.013. Epub 2019 Nov 14. Eur Neuropsychopharmacol. 2019. PMID: 31734018 Free article.
Differential effects of antipsychotic and propsychotic drugs on prepulse inhibition and locomotor activity in Roman high- (RHA) and low-avoidance (RLA) rats.
Oliveras I, Sánchez-González A, Sampedro-Viana D, Piludu MA, Río-Alamos C, Giorgi O, Corda MG, Aznar S, González-Maeso J, Gerbolés C, Blázquez G, Cañete T, Tobeña A, Fernández-Teruel A. Oliveras I, et al. Psychopharmacology (Berl). 2017 Mar;234(6):957-975. doi: 10.1007/s00213-017-4534-8. Epub 2017 Feb 2. Psychopharmacology (Berl). 2017. PMID: 28154892 Free PMC article.
113 results