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Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.
Spilman PR, Corset V, Gorostiza O, Poksay KS, Galvan V, Zhang J, Rao R, Peters-Libeu C, Vincelette J, McGeehan A, Dvorak-Ewell M, Beyer J, Campagna J, Bankiewicz K, Mehlen P, John V, Bredesen DE. Spilman PR, et al. Among authors: gorostiza o. J Alzheimers Dis. 2016 Mar 8;52(1):223-42. doi: 10.3233/JAD-151046. J Alzheimers Dis. 2016. PMID: 27060954
Paradoxical effect of TrkA inhibition in Alzheimer's disease models.
Zhang Q, Descamps O, Hart MJ, Poksay KS, Spilman P, Kane DJ, Gorostiza O, John V, Bredesen DE. Zhang Q, et al. Among authors: gorostiza o. J Alzheimers Dis. 2014;40(3):605-617. doi: 10.3233/JAD-130017. J Alzheimers Dis. 2014. PMID: 24531152 Free PMC article.
A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease.
Cottrell BA, Galvan V, Banwait S, Gorostiza O, Lombardo CR, Williams T, Schilling B, Peel A, Gibson B, Koo EH, Link CD, Bredesen DE. Cottrell BA, et al. Among authors: gorostiza o. Ann Neurol. 2005 Aug;58(2):277-89. doi: 10.1002/ana.20554. Ann Neurol. 2005. PMID: 16049941 Free PMC article.
In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.
Butterfield DA, Galvan V, Lange MB, Tang H, Sowell RA, Spilman P, Fombonne J, Gorostiza O, Zhang J, Sultana R, Bredesen DE. Butterfield DA, et al. Among authors: gorostiza o. Free Radic Biol Med. 2010 Jan 1;48(1):136-44. doi: 10.1016/j.freeradbiomed.2009.10.035. Epub 2009 Oct 23. Free Radic Biol Med. 2010. PMID: 19854267 Free PMC article.
The small co-chaperone p23 overexpressing transgenic mouse.
Zhang J, Spilman P, Chen S, Gorostiza O, Matalis A, Niazi K, Bredesen DE, Rao RV. Zhang J, et al. Among authors: gorostiza o. J Neurosci Methods. 2013 Jan 30;212(2):190-4. doi: 10.1016/j.jneumeth.2012.09.022. Epub 2012 Sep 27. J Neurosci Methods. 2013. PMID: 23022695 Free PMC article.
22 results