Gould CM - Search Results

1

Gould CM, Newton AC. Gould CM, et al. Curr Drug Targets. 2008 Aug;9(8):614-25. doi: 10.2174/138945008785132411. Curr Drug Targets. 2008. PMID: 18691009 Free PMC article. Review.

2

The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.

Gould CM, Kannan N, Taylor SS, Newton AC. Gould CM, et al. J Biol Chem. 2009 Feb 20;284(8):4921-35. doi: 10.1074/jbc.M808436200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19091746 Free PMC article.

3

Interaction with AKAP79 modifies the cellular pharmacology of PKC.

Hoshi N, Langeberg LK, Gould CM, Newton AC, Scott JD. Hoshi N, et al. Among authors: gould cm. Mol Cell. 2010 Feb 26;37(4):541-50. doi: 10.1016/j.molcel.2010.01.014. Mol Cell. 2010. PMID: 20188672 Free PMC article.

4

Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form.

Gould CM, Antal CE, Reyes G, Kunkel MT, Adams RA, Ziyar A, Riveros T, Newton AC. Gould CM, et al. J Biol Chem. 2011 Aug 19;286(33):28922-28930. doi: 10.1074/jbc.M111.272526. Epub 2011 Jun 29. J Biol Chem. 2011. PMID: 21715334 Free PMC article.

5

Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase.

Chen D, Gould C, Garza R, Gao T, Hampton RY, Newton AC. Chen D, et al. J Biol Chem. 2007 Nov 16;282(46):33776-33787. doi: 10.1074/jbc.M703320200. Epub 2007 Sep 24. J Biol Chem. 2007. PMID: 17893151 Free article.

6

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.

Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, Stefan E, Taylor SS, Newton AC. Baffi TR, et al. Among authors: gould cm. Sci Signal. 2021 Apr 13;14(678):eabe4509. doi: 10.1126/scisignal.abe4509. Sci Signal. 2021. PMID: 33850054 Free PMC article.

7

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.

Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E. Facchinetti V, et al. EMBO J. 2008 Jul 23;27(14):1932-43. doi: 10.1038/emboj.2008.120. Epub 2008 Jun 19. EMBO J. 2008. PMID: 18566586 Free PMC article.

8

Regulation of invadopodia by the tumor microenvironment.

Gould CM, Courtneidge SA. Gould CM, et al. Cell Adh Migr. 2014;8(3):226-35. doi: 10.4161/cam.28346. Cell Adh Migr. 2014. PMID: 24714597 Free PMC article. Review.

9

Designing specific protein kinase inhibitors: insights from computer simulations and comparative sequence/structure analysis.

Gould C, Wong CF. Gould C, et al. Pharmacol Ther. 2002 Feb-Mar;93(2-3):169-78. doi: 10.1016/s0163-7258(02)00186-9. Pharmacol Ther. 2002. PMID: 12191609 Review.

10

Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway.

Hannan KM, Soo P, Wong MS, Lee JK, Hein N, Poh P, Wysoke KD, Williams TD, Montellese C, Smith LK, Al-Obaidi SJ, Núñez-Villacís L, Pavy M, He JS, Parsons KM, Loring KE, Morrison T, Diesch J, Burgio G, Ferreira R, Feng ZP, Gould CM, Madhamshettiwar PB, Flygare J, Gonda TJ, Simpson KJ, Kutay U, Pearson RB, Engel C, Watkins NJ, Hannan RD, George AJ. Hannan KM, et al. Among authors: gould cm. Cell Rep. 2022 Nov 1;41(5):111571. doi: 10.1016/j.celrep.2022.111571. Cell Rep. 2022. PMID: 36323262 Free PMC article.

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