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Patterns and functional implications of rare germline variants across 12 cancer types.
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding L. Lu C, et al. Among authors: govindan r. Nat Commun. 2015 Dec 22;6:10086. doi: 10.1038/ncomms10086. Nat Commun. 2015. PMID: 26689913 Free PMC article.
Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.
Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Minna J, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Liu Y, Viswanathan A, Govindan R, Anderson MW, You M. Wang M, et al. Among authors: govindan r. Cancer Res. 2007 Jan 1;67(1):93-9. doi: 10.1158/0008-5472.CAN-06-2723. Cancer Res. 2007. PMID: 17210687 Free PMC article.
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.
Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M. Vikis H, et al. Among authors: govindan r. Cancer Res. 2007 May 15;67(10):4665-70. doi: 10.1158/0008-5472.CAN-07-0217. Cancer Res. 2007. PMID: 17510392 Free PMC article.
Genomic landscape of non-small cell lung cancer in smokers and never-smokers.
Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, Xiong D, You M, Dooling DJ, Watson M, Mardis ER, Wilson RK. Govindan R, et al. Cell. 2012 Sep 14;150(6):1121-34. doi: 10.1016/j.cell.2012.08.024. Cell. 2012. PMID: 22980976 Free PMC article.
DGIdb: mining the druggable genome.
Griffith M, Griffith OL, Coffman AC, Weible JV, McMichael JF, Spies NC, Koval J, Das I, Callaway MB, Eldred JM, Miller CA, Subramanian J, Govindan R, Kumar RD, Bose R, Ding L, Walker JR, Larson DE, Dooling DJ, Smith SM, Ley TJ, Mardis ER, Wilson RK. Griffith M, et al. Among authors: govindan r. Nat Methods. 2013 Dec;10(12):1209-10. doi: 10.1038/nmeth.2689. Epub 2013 Oct 13. Nat Methods. 2013. PMID: 24122041 Free PMC article.
cDNA hybrid capture improves transcriptome analysis on low-input and archived samples.
Cabanski CR, Magrini V, Griffith M, Griffith OL, McGrath S, Zhang J, Walker J, Ly A, Demeter R, Fulton RS, Pong WW, Gutmann DH, Govindan R, Mardis ER, Maher CA. Cabanski CR, et al. Among authors: govindan r. J Mol Diagn. 2014 Jul;16(4):440-51. doi: 10.1016/j.jmoldx.2014.03.004. Epub 2014 May 9. J Mol Diagn. 2014. PMID: 24814956 Free PMC article.
Comprehensive molecular profiling of lung adenocarcinoma.
Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9. Nature. 2014. PMID: 25079552 Free PMC article.
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.
Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J; Cancer Genome Atlas Research Network; Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V. Saltz J, et al. Cell Rep. 2018 Apr 3;23(1):181-193.e7. doi: 10.1016/j.celrep.2018.03.086. Cell Rep. 2018. PMID: 29617659 Free PMC article.
630 results