Grahn THM - Search Results

1

BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism.

Luo L, Sun W, Zhu W, Li S, Zhang W, Xu X, Fang D, Grahn THM, Jiang L, Zheng Y. Luo L, et al. Among authors: grahn thm. Cell Death Dis. 2021 Feb 10;12(2):169. doi: 10.1038/s41419-021-03456-7. Cell Death Dis. 2021. PMID: 33568627 Free PMC article.

2

Anticancer effects of baicalein on hepatocellular carcinoma cells.

Zheng YH, Yin LH, Grahn TH, Ye AF, Zhao YR, Zhang QY. Zheng YH, et al. Phytother Res. 2014 Sep;28(9):1342-8. doi: 10.1002/ptr.5135. Epub 2014 Mar 4. Phytother Res. 2014. PMID: 24596136

3

BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin.

Zheng YH, Hu WJ, Chen BC, Grahn TH, Zhao YR, Bao HL, Zhu YF, Zhang QY. Zheng YH, et al. Liver Int. 2016 Dec;36(12):1836-1847. doi: 10.1111/liv.13178. Epub 2016 Jun 20. Liver Int. 2016. PMID: 27246112

4

Human CIDEC transgene improves lipid metabolism and protects against high-fat diet-induced glucose intolerance in mice.

Gupta A, Balakrishnan B, Karki S, Slayton M, Jash S, Banerjee S, Grahn THM, Jambunathan S, Disney S, Hussein H, Kong D, Lowell BB, Natarajan P, Reddy UK, Gokce N, Sharma VM, Puri V. Gupta A, et al. Among authors: grahn thm. J Biol Chem. 2022 Sep;298(9):102347. doi: 10.1016/j.jbc.2022.102347. Epub 2022 Aug 11. J Biol Chem. 2022. PMID: 35963433 Free PMC article.

5

Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34⁺ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector.

Liu Y, Dahl M, Debnath S, Rothe M, Smith EM, Grahn THM, Warsi S, Chen J, Flygare J, Schambach A, Karlsson S. Liu Y, et al. Among authors: grahn thm. Haematologica. 2022 Feb 1;107(2):446-456. doi: 10.3324/haematol.2020.269142. Haematologica. 2022. PMID: 33440921 Free PMC article.

6

Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes.

Grahn THM, Kaur R, Yin J, Schweiger M, Sharma VM, Lee MJ, Ido Y, Smas CM, Zechner R, Lass A, Puri V. Grahn THM, et al. J Biol Chem. 2014 Apr 25;289(17):12029-12039. doi: 10.1074/jbc.M113.539890. Epub 2014 Mar 13. J Biol Chem. 2014. PMID: 24627478 Free PMC article.

7

FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes.

Grahn TH, Zhang Y, Lee MJ, Sommer AG, Mostoslavsky G, Fried SK, Greenberg AS, Puri V. Grahn TH, et al. Biochem Biophys Res Commun. 2013 Mar 8;432(2):296-301. doi: 10.1016/j.bbrc.2013.01.113. Epub 2013 Feb 8. Biochem Biophys Res Commun. 2013. PMID: 23399566 Free PMC article.

8

S100A6 is a critical regulator of hematopoietic stem cells.

Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Garcia SC, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Leukemia. 2020 Dec;34(12):3323-3337. doi: 10.1038/s41375-020-0901-2. Epub 2020 Jun 19. Leukemia. 2020. PMID: 32555370 Free PMC article.

9

Correction: S100A6 is a critical regulator of hematopoietic stem cells.

Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Capellera-Garcia S, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Leukemia. 2020 Dec;34(12):3439. doi: 10.1038/s41375-020-0971-1. Leukemia. 2020. PMID: 32665696 Free PMC article.

10

The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation.

Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM. Acosta H, et al. Development. 2015 Mar 15;142(6):1146-58. doi: 10.1242/dev.113886. Development. 2015. PMID: 25758225

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