Grant S - Search Results

1

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.

Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P. Qiao L, et al. Among authors: grant s. Hepatology. 2002 Apr;35(4):779-89. doi: 10.1053/jhep.2002.32533. Hepatology. 2002. PMID: 11915023

2

Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.

Jarvis WD, Fornari FA Jr, Browning JL, Gewirtz DA, Kolesnick RN, Grant S. Jarvis WD, et al. Among authors: grant s. J Biol Chem. 1994 Dec 16;269(50):31685-92. J Biol Chem. 1994. PMID: 7989341 Free article.

Prior studies demonstrated that increased intracellular availability of ceramide induces apoptotic DNA degradation and cell death in the human leukemia cell lines HL-60 and U937 (Jarvis, W. D., Kolesnick, R. N., Fornari, F. A., Traylor, R. S., Gewirtz, D. A., and Grant …

Prior studies demonstrated that increased intracellular availability of ceramide induces apoptotic DNA degradation and cell death in the hum …

3

Positive and negative regulation of JNK1 by protein kinase C and p42(MAP kinase) in adult rat hepatocytes.

Jarvis WD, Auer KL, Spector M, Kunos G, Grant S, Hylemon P, Mikkelsen R, Dent P. Jarvis WD, et al. Among authors: grant s. FEBS Lett. 1997 Jul 21;412(1):9-14. doi: 10.1016/s0014-5793(97)00705-9. FEBS Lett. 1997. PMID: 9257680 Free article.

4

Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.

Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S. Wang S, et al. Among authors: grant s. Mol Pharmacol. 1997 Dec;52(6):1000-9. doi: 10.1124/mol.52.6.1000. Mol Pharmacol. 1997. PMID: 9396780

5

Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine.

Jarvis WD, Fornari FA Jr, Auer KL, Freemerman AJ, Szabo E, Birrer MJ, Johnson CR, Barbour SE, Dent P, Grant S. Jarvis WD, et al. Among authors: grant s. Mol Pharmacol. 1997 Dec;52(6):935-47. doi: 10.1124/mol.52.6.935. Mol Pharmacol. 1997. PMID: 9415703

6

Effect of bryostatin 1 on taxol-induced apoptosis and cytotoxicity in human leukemia cells (U937).

Wang S, Guo CY, Castillo A, Dent P, Grant S. Wang S, et al. Among authors: grant s. Biochem Pharmacol. 1998 Sep 1;56(5):635-44. doi: 10.1016/s0006-2952(98)00188-9. Biochem Pharmacol. 1998. PMID: 9783732

7

Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling.

Jarvis WD, Fornari FA Jr, Tombes RM, Erukulla RK, Bittman R, Schwartz GK, Dent P, Grant S. Jarvis WD, et al. Among authors: grant s. Mol Pharmacol. 1998 Nov;54(5):844-56. doi: 10.1124/mol.54.5.844. Mol Pharmacol. 1998. PMID: 9804619

8

The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity.

Dent P, Jarvis WD, Birrer MJ, Fisher PB, Schmidt-Ullrich RK, Grant S. Dent P, et al. Among authors: grant s. Leukemia. 1998 Dec;12(12):1843-50. doi: 10.1038/sj.leu.2401222. Leukemia. 1998. PMID: 9844914 Review.

9

Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.

Wang Z, Van Tuyle G, Conrad D, Fisher PB, Dent P, Grant S. Wang Z, et al. Among authors: grant s. Cancer Res. 1999 Mar 15;59(6):1259-67. Cancer Res. 1999. PMID: 10096557

10

Inhibition of the MAPK pathway abrogates BCL2-mediated survival of leukemia cells after exposure to low-dose ionizing radiation.

Vrana JA, Grant S, Dent P. Vrana JA, et al. Among authors: grant s. Radiat Res. 1999 May;151(5):559-69. Radiat Res. 1999. PMID: 10319729

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