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Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: discovery and computational modeling of a new series of ligands with nanomolar affinity.
Anighoro A, Graziani D, Bettinelli I, Cilia A, De Toma C, Longhi M, Mangiarotti F, Menegon S, Pirona L, Poggesi E, Riva C, Rastelli G. Anighoro A, et al. Among authors: graziani d. Bioorg Med Chem. 2015 Jul 1;23(13):3040-58. doi: 10.1016/j.bmc.2015.05.008. Epub 2015 May 12. Bioorg Med Chem. 2015. PMID: 26014480
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5.
Graziani D, Caligari S, Callegari E, De Toma C, Longhi M, Frigerio F, Dilernia R, Menegon S, Pinzi L, Pirona L, Tazzari V, Valsecchi AE, Vistoli G, Rastelli G, Riva C. Graziani D, et al. J Med Chem. 2019 Feb 14;62(3):1246-1273. doi: 10.1021/acs.jmedchem.8b01226. Epub 2019 Jan 28. J Med Chem. 2019. PMID: 30624919
Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412).
Giardina GA, Raveglia LF, Grugni M, Sarau HM, Farina C, Medhurst AD, Graziani D, Schmidt DB, Rigolio R, Luttmann M, Cavagnera S, Foley JJ, Vecchietti V, Hay DW. Giardina GA, et al. Among authors: graziani d. J Med Chem. 1999 Mar 25;42(6):1053-65. doi: 10.1021/jm980633c. J Med Chem. 1999. PMID: 10090788
Is early continence recovery related to the length of spared urethra? A prospective multicenter study comparing preoperative MRI and histologic specimen measurements after robotic radical prostatectomy.
Valenzi FM, Fuschi A, Al Salhi Y, Sequi MB, Suraci PP, Pacini M, Scalzo S, Rera OA, Antonioni A, Graziani D, Martino G, Candita G, Gianfrancesco F, Zucchi A, Lombardo R, De Nunzio C, Cicione A, Bozzini G, Rengo M, Capodiferro P, Sciarra A, Petrozza V, Carbone A, Pastore AL. Valenzi FM, et al. Among authors: graziani d. Eur J Surg Oncol. 2024 Apr 2;50(6):108319. doi: 10.1016/j.ejso.2024.108319. Online ahead of print. Eur J Surg Oncol. 2024. PMID: 38603868 Free article.
Phylogenetic Inferences Based on Distinct Molecular Markers Confirm a Novel Babesia Species (Babesia goianiaensis nov. sp.) in Capybaras (Hydrochoerus hydrochaeris) and Associated Ticks.
Krawczak FDS, Calchi AC, Neves LC, Dias SA, da Silva BBF, Paula WVF, de Paula LGF, Tavares MA, Pádua GT, de Lima NJ, Cardoso ERN, Graziani D, Dantas-Torres F, André MR. Krawczak FDS, et al. Among authors: graziani d. Microorganisms. 2023 Aug 6;11(8):2022. doi: 10.3390/microorganisms11082022. Microorganisms. 2023. PMID: 37630582 Free PMC article.
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