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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: graziano vr. Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028. Epub 2020 Oct 20. Cell. 2021. PMID: 33147444 Free PMC article.
Norovirus Attachment and Entry.
Graziano VR, Wei J, Wilen CB. Graziano VR, et al. Viruses. 2019 May 30;11(6):495. doi: 10.3390/v11060495. Viruses. 2019. PMID: 31151248 Free PMC article. Review.
The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon.
Grau KR, Zhu S, Peterson ST, Helm EW, Philip D, Phillips M, Hernandez A, Turula H, Frasse P, Graziano VR, Wilen CB, Wobus CE, Baldridge MT, Karst SM. Grau KR, et al. Among authors: graziano vr. Nat Microbiol. 2020 Jan;5(1):84-92. doi: 10.1038/s41564-019-0602-7. Epub 2019 Nov 25. Nat Microbiol. 2020. PMID: 31768030 Free PMC article.
CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus.
Graziano VR, Walker FC, Kennedy EA, Wei J, Ettayebi K, Strine MS, Filler RB, Hassan E, Hsieh LL, Kim AS, Kolawole AO, Wobus CE, Lindesmith LC, Baric RS, Estes MK, Orchard RC, Baldridge MT, Wilen CB. Graziano VR, et al. PLoS Pathog. 2020 Apr 6;16(4):e1008242. doi: 10.1371/journal.ppat.1008242. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32251490 Free PMC article.
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection.
Wei J, Alfajaro MM, Hanna RE, DeWeirdt PC, Strine MS, Lu-Culligan WJ, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Gasque V, de Miguel F, Chen H, Oguntuyo K, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach B, Politi K, van Dijk D, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: graziano vr. bioRxiv [Preprint]. 2020 Jun 17:2020.06.16.155101. doi: 10.1101/2020.06.16.155101. bioRxiv. 2020. PMID: 32869025 Free PMC article. Updated. Preprint.
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.
Wei J, Alfajaro MM, Cai WL, Graziano VR, Strine MS, Filler RB, Biering SB, Sarnik SA, Patel S, Menasche BL, Compton SR, Konermann S, Hsu PD, Orchard RC, Yan Q, Wilen CB. Wei J, et al. Among authors: graziano vr. PLoS Pathog. 2023 Jul 6;19(7):e1011351. doi: 10.1371/journal.ppat.1011351. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37410700 Free PMC article.
Intestinal tuft cell immune privilege enables norovirus persistence.
Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Strine MS, et al. Among authors: graziano vr. Sci Immunol. 2024 Mar 22;9(93):eadi7038. doi: 10.1126/sciimmunol.adi7038. Epub 2024 Mar 22. Sci Immunol. 2024. PMID: 38517952
Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.
Walker FC, Hassan E, Peterson ST, Rodgers R, Schriefer LA, Thompson CE, Li Y, Kalugotla G, Blum-Johnston C, Lawrence D, McCune BT, Graziano VR, Lushniak L, Lee S, Roth AN, Karst SM, Nice TJ, Miner JJ, Wilen CB, Baldridge MT. Walker FC, et al. Among authors: graziano vr. PLoS Pathog. 2021 Mar 11;17(3):e1009402. doi: 10.1371/journal.ppat.1009402. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33705489 Free PMC article.
11 results