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Page 1
Selective in vitro anti-cancer activity of non-alkylating minor groove binders.
Nichol RJO, Khalaf AI, Sooda K, Hussain O, Griffiths HBS, Phillips R, Javid FA, Suckling CJ, Allison SJ, Scott FJ. Nichol RJO, et al. Among authors: griffiths hbs. Medchemcomm. 2019 Jul 18;10(9):1620-1634. doi: 10.1039/c9md00268e. eCollection 2019 Sep 1. Medchemcomm. 2019. PMID: 32952999 Free PMC article.
Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells.
da Silva B, Irving BK, Polson ES, Droop A, Griffiths HBS, Mathew RK, Stead LF, Marrison J, Williams C, Williams J, Short SC, Scarcia M, O'Toole PJ, Allison SJ, Mavria G, Wurdak H. da Silva B, et al. Among authors: griffiths hbs. J Cell Sci. 2019 Oct 10;132(19):jcs228452. doi: 10.1242/jcs.228452. J Cell Sci. 2019. PMID: 31515278 Free article.
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.
Polson ES, Kuchler VB, Abbosh C, Ross EM, Mathew RK, Beard HA, da Silva B, Holding AN, Ballereau S, Chuntharpursat-Bon E, Williams J, Griffiths HBS, Shao H, Patel A, Davies AJ, Droop A, Chumas P, Short SC, Lorger M, Gestwicki JE, Roberts LD, Bon RS, Allison SJ, Zhu S, Markowetz F, Wurdak H. Polson ES, et al. Among authors: griffiths hbs. Sci Transl Med. 2018 Aug 15;10(454):eaar2718. doi: 10.1126/scitranslmed.aar2718. Sci Transl Med. 2018. PMID: 30111643 Free article.
Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells.
Allison SJ, Cooke D, Davidson FS, Elliott PIP, Faulkner RA, Griffiths HBS, Harper OJ, Hussain O, Owen-Lynch PJ, Phillips RM, Rice CR, Shepherd SL, Wheelhouse RT. Allison SJ, et al. Among authors: griffiths hbs. Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9799-9804. doi: 10.1002/anie.201805510. Epub 2018 Jul 3. Angew Chem Int Ed Engl. 2018. PMID: 29863754