Gromak N - Search Results

1

Hypoxia-induced SETX links replication stress with the unfolded protein response.

Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Ramachandran S, et al. Among authors: gromak n. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. Nat Commun. 2021. PMID: 34140498 Free PMC article.

2

Increased global transcription activity as a mechanism of replication stress in cancer.

Kotsantis P, Silva LM, Irmscher S, Jones RM, Folkes L, Gromak N, Petermann E. Kotsantis P, et al. Among authors: gromak n. Nat Commun. 2016 Oct 11;7:13087. doi: 10.1038/ncomms13087. Nat Commun. 2016. PMID: 27725641 Free PMC article.

3

Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration.

Groh M, Albulescu LO, Cristini A, Gromak N. Groh M, et al. Among authors: gromak n. J Mol Biol. 2017 Oct 27;429(21):3181-3195. doi: 10.1016/j.jmb.2016.10.021. Epub 2016 Oct 19. J Mol Biol. 2017. PMID: 27771483 Review.

4

RNase H2, mutated in Aicardi-Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation.

Cristini A, Tellier M, Constantinescu F, Accalai C, Albulescu LO, Heiringhoff R, Bery N, Sordet O, Murphy S, Gromak N. Cristini A, et al. Among authors: gromak n. Nat Commun. 2022 May 26;13(1):2961. doi: 10.1038/s41467-022-30604-0. Nat Commun. 2022. PMID: 35618715 Free PMC article.

5

R-Loop Immunoprecipitation: A Method to Detect R-Loop Interacting Factors.

Beghè C, Gromak N. Beghè C, et al. Among authors: gromak n. Methods Mol Biol. 2022;2528:215-237. doi: 10.1007/978-1-0716-2477-7_14. Methods Mol Biol. 2022. PMID: 35704194

6

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops.

Ma TS, Worth KR, Maher C, Ng N, Beghè C, Gromak N, Rose AM, Hammond EM. Ma TS, et al. Among authors: gromak n. Nucleic Acids Res. 2023 Nov 27;51(21):11584-11599. doi: 10.1093/nar/gkad858. Nucleic Acids Res. 2023. PMID: 37843099 Free PMC article.

7

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.

West S, Gromak N, Proudfoot NJ. West S, et al. Among authors: gromak n. Nature. 2004 Nov 25;432(7016):522-5. doi: 10.1038/nature03035. Nature. 2004. PMID: 15565158

8

Primary microRNA transcripts are processed co-transcriptionally.

Morlando M, Ballarino M, Gromak N, Pagano F, Bozzoni I, Proudfoot NJ. Morlando M, et al. Among authors: gromak n. Nat Struct Mol Biol. 2008 Sep;15(9):902-9. doi: 10.1038/nsmb.1475. Nat Struct Mol Biol. 2008. PMID: 19172742 Free PMC article.

9

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination.

Skourti-Stathaki K, Proudfoot NJ, Gromak N. Skourti-Stathaki K, et al. Among authors: gromak n. Mol Cell. 2011 Jun 24;42(6):794-805. doi: 10.1016/j.molcel.2011.04.026. Mol Cell. 2011. PMID: 21700224 Free PMC article.

10

Out of balance: R-loops in human disease.

Groh M, Gromak N. Groh M, et al. Among authors: gromak n. PLoS Genet. 2014 Sep 18;10(9):e1004630. doi: 10.1371/journal.pgen.1004630. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25233079 Free PMC article. Review.

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