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A mechanism for P-glycoprotein action in multidrug resistance: are we there yet?
Ruetz S, Gros P. Ruetz S, et al. Among authors: gros p. Trends Pharmacol Sci. 1994 Jul;15(7):260-3. doi: 10.1016/0165-6147(94)90322-0. Trends Pharmacol Sci. 1994. PMID: 7940990 Review.
Multidrug resistance is associated with the overexpression of P-glycoprotein, a membrane glycoprotein. The mechanism by which P-glycoprotein confers to cells the capacity to resist cytotoxic attack by structurally unrelated drugs has remained difficult to decipher. …
Multidrug resistance is associated with the overexpression of P-glycoprotein, a membrane glycoprotein. The mechanism by which P
Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520.
Raymond M, Ruetz S, Thomas DY, Gros P. Raymond M, et al. Among authors: gros p. Mol Cell Biol. 1994 Jan;14(1):277-86. doi: 10.1128/mcb.14.1.277-286.1994. Mol Cell Biol. 1994. PMID: 7505392 Free PMC article.
We have recently reported that expression in yeast cells of P-glycoprotein (P-gp) encoded by the mouse multidrug resistance mdr3 gene (Mdr3) can complement a null ste6 mutation (M. Raymond, P. Gros, M. Whiteway, and D. Y. Thomas, Science 256:232-234, 1 …
We have recently reported that expression in yeast cells of P-glycoprotein (P-gp) encoded by the mouse multidrug resistance md …
773 results