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GP130 activation induces myeloma and collaborates with MYC.
Dechow T, Steidle S, Götze KS, Rudelius M, Behnke K, Pechloff K, Kratzat S, Bullinger L, Fend F, Soberon V, Mitova N, Li Z, Thaler M, Bauer J, Pietschmann E, Albers C, Grundler R, Schmidt-Supprian M, Ruland J, Peschel C, Duyster J, Rose-John S, Bassermann F, Keller U. Dechow T, et al. Among authors: grundler r. J Clin Invest. 2014 Dec;124(12):5263-74. doi: 10.1172/JCI69094. Epub 2014 Nov 10. J Clin Invest. 2014. PMID: 25384216 Free PMC article. Clinical Trial.
ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer.
Baumgart A, Seidl S, Vlachou P, Michel L, Mitova N, Schatz N, Specht K, Koch I, Schuster T, Grundler R, Kremer M, Fend F, Siveke JT, Peschel C, Duyster J, Dechow T. Baumgart A, et al. Among authors: grundler r. Cancer Res. 2010 Jul 1;70(13):5368-78. doi: 10.1158/0008-5472.CAN-09-3763. Epub 2010 Jun 15. Cancer Res. 2010. PMID: 20551051
SRC is a signaling mediator in FLT3-ITD- but not in FLT3-TKD-positive AML.
Leischner H, Albers C, Grundler R, Razumovskaya E, Spiekermann K, Bohlander S, Rönnstrand L, Götze K, Peschel C, Duyster J. Leischner H, et al. Among authors: grundler r. Blood. 2012 Apr 26;119(17):4026-33. doi: 10.1182/blood-2011-07-365726. Epub 2012 Mar 12. Blood. 2012. PMID: 22411868 Free article.
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