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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Reyes A, Wang Q, Weichenhan D, Lier A, von Paleske L, Renders S, Wünsche P, Zeisberger P, Brocks D, Gu L, Herrmann C, Haas S, Essers MAG, Brors B, Eils R, Huber W, Milsom MD, Plass C, Krijgsveld J, Trumpp A. Cabezas-Wallscheid N, et al. Among authors: gu l. Cell Stem Cell. 2014 Oct 2;15(4):507-522. doi: 10.1016/j.stem.2014.07.005. Epub 2014 Aug 21. Cell Stem Cell. 2014. PMID: 25158935 Free article.
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Lipka DB, Wang Q, Cabezas-Wallscheid N, Klimmeck D, Weichenhan D, Herrmann C, Lier A, Brocks D, von Paleske L, Renders S, Wünsche P, Zeisberger P, Gu L, Haas S, Essers MA, Brors B, Eils R, Trumpp A, Milsom MD, Plass C. Lipka DB, et al. Among authors: gu l. Cell Cycle. 2014;13(22):3476-87. doi: 10.4161/15384101.2014.973334. Cell Cycle. 2014. PMID: 25483069 Free PMC article.
Tagmentation-based whole-genome bisulfite sequencing.
Wang Q, Gu L, Adey A, Radlwimmer B, Wang W, Hovestadt V, Bähr M, Wolf S, Shendure J, Eils R, Plass C, Weichenhan D. Wang Q, et al. Among authors: gu l. Nat Protoc. 2013 Oct;8(10):2022-32. doi: 10.1038/nprot.2013.118. Epub 2013 Sep 26. Nat Protoc. 2013. PMID: 24071908
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.
Oakes CC, Seifert M, Assenov Y, Gu L, Przekopowitz M, Ruppert AS, Wang Q, Imbusch CD, Serva A, Koser SD, Brocks D, Lipka DB, Bogatyrova O, Weichenhan D, Brors B, Rassenti L, Kipps TJ, Mertens D, Zapatka M, Lichter P, Döhner H, Küppers R, Zenz T, Stilgenbauer S, Byrd JC, Plass C. Oakes CC, et al. Among authors: gu l. Nat Genet. 2016 Mar;48(3):253-64. doi: 10.1038/ng.3488. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780610 Free PMC article.
Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children.
Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R, Lehmann I. Bauer T, et al. Among authors: gu z, gu l. Mol Syst Biol. 2016 Mar 24;12(3):861. doi: 10.15252/msb.20156520. Mol Syst Biol. 2016. PMID: 27013061 Free PMC article.
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Sonnet M, Claus R, Becker N, Zucknick M, Petersen J, Lipka DB, Oakes CC, Andrulis M, Lier A, Milsom MD, Witte T, Gu L, Kim-Wanner SZ, Schirmacher P, Wulfert M, Gattermann N, Lübbert M, Rosenbauer F, Rehli M, Bullinger L, Weichenhan D, Plass C. Sonnet M, et al. Among authors: gu l. Genome Med. 2014 Apr 30;6(4):34. doi: 10.1186/gm551. eCollection 2014. Genome Med. 2014. PMID: 24944583 Free PMC article.
Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation.
Trump S, Bieg M, Gu Z, Thürmann L, Bauer T, Bauer M, Ishaque N, Röder S, Gu L, Herberth G, Lawerenz C, Borte M, Schlesner M, Plass C, Diessl N, Eszlinger M, Mücke O, Elvers HD, Wissenbach DK, von Bergen M, Herrmann C, Weichenhan D, Wright RJ, Lehmann I, Eils R. Trump S, et al. Among authors: gu z, gu l. Sci Rep. 2016 Jun 28;6:28616. doi: 10.1038/srep28616. Sci Rep. 2016. PMID: 27349968 Free PMC article. Clinical Trial.
Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.
Goeppert B, Toth R, Singer S, Albrecht T, Lipka DB, Lutsik P, Brocks D, Baehr M, Muecke O, Assenov Y, Gu L, Endris V, Stenzinger A, Mehrabi A, Schirmacher P, Plass C, Weichenhan D, Roessler S. Goeppert B, et al. Among authors: gu l. Hepatology. 2019 May;69(5):2091-2106. doi: 10.1002/hep.30493. Epub 2019 Feb 28. Hepatology. 2019. PMID: 30615206 Free PMC article.
6,541 results