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Hypoxic selectivity and solubility--investigating the properties of A-ring substituted nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-ones (nitroCBIs) as hypoxia-activated prodrugs for antitumor therapy.
Tercel M, Yang S, Atwell GJ, Smith E, Gu Y, Anderson RF, Denny WA, Wilson WR, Pruijn FB. Tercel M, et al. Among authors: gu y. Bioorg Med Chem. 2010 Jul 15;18(14):4997-5006. doi: 10.1016/j.bmc.2010.06.001. Epub 2010 Jun 8. Bioorg Med Chem. 2010. PMID: 20580559
Novel nitroimidazole alkylsulfonamides as hypoxic cell radiosensitisers.
Bonnet M, Hong CR, Gu Y, Anderson RF, Wilson WR, Pruijn FB, Wang J, Hicks KO, Hay MP. Bonnet M, et al. Among authors: gu y. Bioorg Med Chem. 2014 Apr 1;22(7):2123-32. doi: 10.1016/j.bmc.2014.02.039. Epub 2014 Mar 3. Bioorg Med Chem. 2014. PMID: 24650701
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