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Constitutive protein kinase G activation exacerbates stress-induced cardiomyopathy.
Schwaerzer GK, Casteel DE, Cividini F, Kalyanaraman H, Zhuang S, Gu Y, Dalton ND, Peterson KL, Dillmann WH, Boss GR, Pilz RB. Schwaerzer GK, et al. Among authors: gu y. Br J Pharmacol. 2022 Jun;179(11):2413-2429. doi: 10.1111/bph.15530. Epub 2021 Jun 21. Br J Pharmacol. 2022. PMID: 34000062 Free PMC article.
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function.
Giordano FJ, Gerber HP, Williams SP, VanBruggen N, Bunting S, Ruiz-Lozano P, Gu Y, Nath AK, Huang Y, Hickey R, Dalton N, Peterson KL, Ross J Jr, Chien KR, Ferrara N. Giordano FJ, et al. Among authors: gu y. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5780-5. doi: 10.1073/pnas.091415198. Epub 2001 May 1. Proc Natl Acad Sci U S A. 2001. PMID: 11331753 Free PMC article.
The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity.
Zhang T, Johnson EN, Gu Y, Morissette MR, Sah VP, Gigena MS, Belke DD, Dillmann WH, Rogers TB, Schulman H, Ross J Jr, Brown JH. Zhang T, et al. Among authors: gu y. J Biol Chem. 2002 Jan 11;277(2):1261-7. doi: 10.1074/jbc.M108525200. Epub 2001 Nov 2. J Biol Chem. 2002. PMID: 11694533 Free article.
ErbB2 is essential in the prevention of dilated cardiomyopathy.
Crone SA, Zhao YY, Fan L, Gu Y, Minamisawa S, Liu Y, Peterson KL, Chen J, Kahn R, Condorelli G, Ross J Jr, Chien KR, Lee KF. Crone SA, et al. Among authors: gu y. Nat Med. 2002 May;8(5):459-65. doi: 10.1038/nm0502-459. Nat Med. 2002. PMID: 11984589
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