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Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.
Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges SL Jr, Criswell LA, Moreland LW, Fonseca JE, de Vries N, Stranger BE, De Jager PL, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Padyukov L, Coenen MJ, Karlson EW, Plenge RM. Cui J, et al. Among authors: guchelaar hj. PLoS Genet. 2013 Mar;9(3):e1003394. doi: 10.1371/journal.pgen.1003394. Epub 2013 Mar 28. PLoS Genet. 2013. PMID: 23555300 Free PMC article.
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Apr;54(4):1087-95. doi: 10.1002/art.21726. Arthritis Rheum. 2006. PMID: 16572443 Free article.
Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.
Wessels JA, Kooloos WM, De Jonge R, De Vries-Bouwstra JK, Allaart CF, Linssen A, Collee G, De Sonnaville P, Lindemans J, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032. Arthritis Rheum. 2006. PMID: 16947783 Free article. Clinical Trial.
Genetic markers of treatment response in rheumatoid arthritis.
Wesoly J, Wessels JA, Guchelaar HJ, Huizinga TW. Wesoly J, et al. Among authors: guchelaar hj. Curr Rheumatol Rep. 2006 Oct;8(5):369-77. doi: 10.1007/s11926-006-0068-5. Curr Rheumatol Rep. 2006. PMID: 16973111 Review.
Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.
van der Straaten RJ, Wessels JA, de Vries-Bouwstra JK, Goekoop-Ruiterman YP, Allaart CF, Bogaartz J, Tiller M, Huizinga TW, Guchelaar HJ. van der Straaten RJ, et al. Among authors: guchelaar hj. Pharmacogenomics. 2007 Feb;8(2):141-50. doi: 10.2217/14622416.8.2.141. Pharmacogenomics. 2007. PMID: 17286537 Clinical Trial.
460 results