Guengerich FP - Search Results

1

Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2.

Turesky RJ, Constable A, Fay LB, Guengerich FP. Turesky RJ, et al. Among authors: guengerich fp. Cancer Lett. 1999 Sep 1;143(2):109-12. doi: 10.1016/s0304-3835(99)00137-8. Cancer Lett. 1999. PMID: 10503887

2

Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.

Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP. Turesky RJ, et al. Among authors: guengerich fp. Chem Res Toxicol. 1998 Aug;11(8):925-36. doi: 10.1021/tx980022n. Chem Res Toxicol. 1998. PMID: 9705755

3

Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.

Turesky RJ, Parisod V, Huynh-Ba T, Langouët S, Guengerich FP. Turesky RJ, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Jul;14(7):901-11. doi: 10.1021/tx010035s. Chem Res Toxicol. 2001. PMID: 11453738

4

Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.

Turesky RJ, Guengerich FP, Guillouzo A, Langouët S. Turesky RJ, et al. Among authors: guengerich fp. Mutat Res. 2002 Sep 30;506-507:187-95. doi: 10.1016/s0027-5107(02)00165-3. Mutat Res. 2002. PMID: 12351158

5

Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype.

Guengerich FP, Parikh A, Turesky RJ, Josephy PD. Guengerich FP, et al. Mutat Res. 1999 Jul 16;428(1-2):115-24. doi: 10.1016/s1383-5742(99)00039-3. Mutat Res. 1999. PMID: 10517985 Review.

6

Metabolism of ochratoxin A: absence of formation of genotoxic derivatives by human and rat enzymes.

Gautier J, Richoz J, Welti DH, Markovic J, Gremaud E, Guengerich FP, Turesky RJ. Gautier J, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Jan;14(1):34-45. doi: 10.1021/tx000070j. Chem Res Toxicol. 2001. PMID: 11170506

7

Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.

Langouët S, Welti DH, Kerriguy N, Fay LB, Huynh-Ba T, Markovic J, Guengerich FP, Guillouzo A, Turesky RJ. Langouët S, et al. Among authors: guengerich fp. Chem Res Toxicol. 2001 Feb;14(2):211-21. doi: 10.1021/tx000176e. Chem Res Toxicol. 2001. PMID: 11258970

8

Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes.

Langouët S, Welti DH, Kerriguy N, Fay LB, Guengerich FP, Guillouzo A, Turesky RJ. Langouët S, et al. Among authors: guengerich fp. Adv Exp Med Biol. 2001;500:459-62. doi: 10.1007/978-1-4615-0667-6_69. Adv Exp Med Biol. 2001. PMID: 11764981 No abstract available.

9

The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.

Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. Christov PP, et al. Among authors: guengerich fp. Chem Res Toxicol. 2010 Jun 21;23(6):1076-88. doi: 10.1021/tx100053n. Chem Res Toxicol. 2010. PMID: 20377178 Free PMC article.

10

Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes.

Hammons GJ, Milton D, Stepps K, Guengerich FP, Tukey RH, Kadlubar FF. Hammons GJ, et al. Among authors: guengerich fp. Carcinogenesis. 1997 Apr;18(4):851-4. doi: 10.1093/carcin/18.4.851. Carcinogenesis. 1997. PMID: 9111224

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