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Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T.
Burga RA, Thorn M, Point GR, Guha P, Nguyen CT, Licata LA, DeMatteo RP, Ayala A, Joseph Espat N, Junghans RP, Katz SC. Burga RA, et al. Among authors: guha p. Cancer Immunol Immunother. 2015 Jul;64(7):817-29. doi: 10.1007/s00262-015-1692-6. Epub 2015 Apr 8. Cancer Immunol Immunother. 2015. PMID: 25850344 Free PMC article.
HITM-SURE: Hepatic immunotherapy for metastases phase Ib anti-CEA CAR-T study utilizing pressure enabled drug delivery.
Katz SC, Moody AE, Guha P, Hardaway JC, Prince E, LaPorte J, Stancu M, Slansky JE, Jordan KR, Schulick RD, Knight R, Saied A, Armenio V, Junghans RP. Katz SC, et al. Among authors: guha p. J Immunother Cancer. 2020 Aug;8(2):e001097. doi: 10.1136/jitc-2020-001097. J Immunother Cancer. 2020. PMID: 32843493 Free PMC article. Clinical Trial.
266 results