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Structure-Based Drug Discovery of IRE1 Modulators.
Pelizzari Raymundo D, Eriksson LA, Chevet E, Guillory X. Pelizzari Raymundo D, et al. Among authors: guillory x. Methods Mol Biol. 2022;2378:293-315. doi: 10.1007/978-1-0716-1732-8_19. Methods Mol Biol. 2022. PMID: 34985708 Free article.
Pharmacological Targeting of IRE1 in Cancer.
Raymundo DP, Doultsinos D, Guillory X, Carlesso A, Eriksson LA, Chevet E. Raymundo DP, et al. Among authors: guillory x. Trends Cancer. 2020 Dec;6(12):1018-1030. doi: 10.1016/j.trecan.2020.07.006. Epub 2020 Aug 26. Trends Cancer. 2020. PMID: 32861679 Free article. Review.
Structural and molecular bases to IRE1 activity modulation.
Langlais T, Pelizzari-Raymundo D, Mahdizadeh SJ, Gouault N, Carreaux F, Chevet E, Eriksson LA, Guillory X. Langlais T, et al. Among authors: guillory x. Biochem J. 2021 Aug 13;478(15):2953-2975. doi: 10.1042/BCJ20200919. Biochem J. 2021. PMID: 34375386 Free article. Review.
Fragment-based Differential Targeting of PPI Stabilizer Interfaces.
Guillory X, Wolter M, Leysen S, Neves JF, Kuusk A, Genet S, Somsen B, Morrow JK, Rivers E, van Beek L, Patel J, Goodnow R, Schoenherr H, Fuller N, Cao Q, Doveston RG, Brunsveld L, Arkin MR, Castaldi P, Boyd H, Landrieu I, Chen H, Ottmann C. Guillory X, et al. J Med Chem. 2020 Jul 9;63(13):6694-6707. doi: 10.1021/acs.jmedchem.9b01942. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32501690 Free PMC article.
The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
Bier D, Mittal S, Bravo-Rodriguez K, Sowislok A, Guillory X, Briels J, Heid C, Bartel M, Wettig B, Brunsveld L, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. Among authors: guillory x. J Am Chem Soc. 2017 Nov 15;139(45):16256-16263. doi: 10.1021/jacs.7b07939. Epub 2017 Nov 2. J Am Chem Soc. 2017. PMID: 29039919 Free PMC article.
Supramolecular Enhancement of a Natural 14-3-3 Protein Ligand.
Guillory X, Hadrović I, de Vink PJ, Sowislok A, Brunsveld L, Schrader T, Ottmann C. Guillory X, et al. J Am Chem Soc. 2021 Sep 1;143(34):13495-13500. doi: 10.1021/jacs.1c07095. Epub 2021 Aug 24. J Am Chem Soc. 2021. PMID: 34427424
14 results