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Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens.
Gurung P, Malireddi RK, Anand PK, Demon D, Vande Walle L, Liu Z, Vogel P, Lamkanfi M, Kanneganti TD. Gurung P, et al. J Biol Chem. 2012 Oct 5;287(41):34474-83. doi: 10.1074/jbc.M112.401406. Epub 2012 Aug 16. J Biol Chem. 2012. PMID: 22898816 Free PMC article.
Protective roles for caspase-8 and cFLIP in adult homeostasis.
Weinlich R, Oberst A, Dillon CP, Janke LJ, Milasta S, Lukens JR, Rodriguez DA, Gurung P, Savage C, Kanneganti TD, Green DR. Weinlich R, et al. Among authors: gurung p. Cell Rep. 2013 Oct 31;5(2):340-8. doi: 10.1016/j.celrep.2013.08.045. Epub 2013 Oct 3. Cell Rep. 2013. PMID: 24095739 Free PMC article.
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR. Dillon CP, et al. Among authors: gurung p. Cell. 2014 May 22;157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8. Cell. 2014. PMID: 24813850 Free PMC article.
Dietary modulation of the microbiome affects autoinflammatory disease.
Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD. Lukens JR, et al. Among authors: gurung p. Nature. 2014 Dec 11;516(7530):246-9. doi: 10.1038/nature13788. Epub 2014 Sep 28. Nature. 2014. PMID: 25274309 Free PMC article.
215 results