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2007 3
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Page 1
The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins.
Ecroyd H, Bartelt-Kirbach B, Ben-Zvi A, Bonavita R, Bushman Y, Casarotto E, Cecconi C, Lau WCY, Hibshman JD, Joosten J, Kimonis V, Klevit R, Liberek K, McMenimen KA, Miwa T, Mogk A, Montepietra D, Peters C, Rocchetti MT, Saman D, Sisto A, Secco V, Strauch A, Taguchi H, Tanguay M, Tedesco B, Toth ME, Wang Z, Benesch JLP, Carra S. Ecroyd H, et al. Cell Stress Chaperones. 2023 Nov;28(6):621-629. doi: 10.1007/s12192-023-01360-x. Epub 2023 Jul 18. Cell Stress Chaperones. 2023. PMID: 37462824 Free PMC article. Review.
Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils.
Binger KJ, Ecroyd H, Yang S, Carver JA, Howlett GJ, Griffin MD. Binger KJ, et al. Among authors: ecroyd h. FASEB J. 2013 Mar;27(3):1214-22. doi: 10.1096/fj.12-220657. Epub 2012 Nov 16. FASEB J. 2013. PMID: 23159935
This work reveals previously unrecognized mechanisms of alphaB-c chaperone action in amyloid assembly and fibril dynamics, and provides a rationale for the in vivo colocalization of small heat-shock proteins with amyloid deposits.-Binger, K. J., Ecroyd, H., Yang, S., Carve …
This work reveals previously unrecognized mechanisms of alphaB-c chaperone action in amyloid assembly and fibril dynamics, and provides a ra …
Role of the epididymis in sperm competition.
Jones RC, Dacheux JL, Nixon B, Ecroyd HW. Jones RC, et al. Among authors: ecroyd hw. Asian J Androl. 2007 Jul;9(4):493-9. doi: 10.1111/j.1745-7262.2007.00284.x. Asian J Androl. 2007. PMID: 17589786 Free article. Review.
A unique example of sperm cooperation in monotremes is used as evidence that the epididymis produces sperm competition proteins to form groups of 100 sperm into bundles that have a forward motility nearly thrice that of individual spermatozoa. As it required 3-h incubation …
A unique example of sperm cooperation in monotremes is used as evidence that the epididymis produces sperm competition proteins to form grou …
Testicular descent, sperm maturation and capacitation. Lessons from our most distant relatives, the monotremes.
Ecroyd H, Nixon B, Dacheux JL, Jones RC. Ecroyd H, et al. Reprod Fertil Dev. 2009;21(8):992-1001. doi: 10.1071/RD09081. Reprod Fertil Dev. 2009. PMID: 19874723 Review.
Bundle formation involves a highly organised interaction with epididymal proteins, and the bundles persist during incubation in vitro, except in specialised medium, in which spermatozoa separate after 2-3 h incubation. It is suggested that this represents an early form of …
Bundle formation involves a highly organised interaction with epididymal proteins, and the bundles persist during incubation in vitro, excep …
Formation and Dissociation of Sperm Bundles in Monotremes.
Nixon B, Ecroyd H, Dacheux JL, Dacheux F, Labas V, Johnston SD, Jones RC. Nixon B, et al. Among authors: ecroyd h. Biol Reprod. 2016 Oct;95(4):91. doi: 10.1095/biolreprod.116.140491. Epub 2016 Aug 24. Biol Reprod. 2016. PMID: 27557648
The bundles persisted during incubation in vitro for at least 1 h under conditions that capacitate therian spermatozoa, and then underwent a time-dependent dissociation to release spermatozoa capable of fertilization. ...
The bundles persisted during incubation in vitro for at least 1 h under conditions that capacitate therian spermatozoa, and then unde …
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity.
Hochberg GK, Ecroyd H, Liu C, Cox D, Cascio D, Sawaya MR, Collier MP, Stroud J, Carver JA, Baldwin AJ, Robinson CV, Eisenberg DS, Benesch JL, Laganowsky A. Hochberg GK, et al. Among authors: ecroyd h. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1562-70. doi: 10.1073/pnas.1322673111. Epub 2014 Apr 7. Proc Natl Acad Sci U S A. 2014. PMID: 24711386 Free PMC article.
Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins.
Meehan S, Knowles TP, Baldwin AJ, Smith JF, Squires AM, Clements P, Treweek TM, Ecroyd H, Tartaglia GG, Vendruscolo M, Macphee CE, Dobson CM, Carver JA. Meehan S, et al. Among authors: ecroyd h. J Mol Biol. 2007 Sep 14;372(2):470-84. doi: 10.1016/j.jmb.2007.06.060. Epub 2007 Jun 29. J Mol Biol. 2007. PMID: 17662998
We find that the last 12 amino acid residues of the C-terminal region of alphaB-crystallin are predicted from their physico-chemical properties to have a very low propensity to aggregate. (1)H NMR spectroscopy reveals that this hydrophilic C-terminal region is flexible bot …
We find that the last 12 amino acid residues of the C-terminal region of alphaB-crystallin are predicted from their physico-chemical propert …