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Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study.
Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, Morris JC, Kleinberger G, Nellgard B, Vöglein J, Blennow K, Zetterberg H, Ewers M, Jucker M, Levin J, Bateman RJ, Haass C; Dominantly Inherited Alzheimer Network. Morenas-Rodríguez E, et al. Among authors: haass c. Lancet Neurol. 2022 Apr;21(4):329-341. doi: 10.1016/S1474-4422(22)00027-8. Lancet Neurol. 2022. PMID: 35305339 Free PMC article.
Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.
Moehlmann T, Winkler E, Xia X, Edbauer D, Murrell J, Capell A, Kaether C, Zheng H, Ghetti B, Haass C, Steiner H. Moehlmann T, et al. Among authors: haass c. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8025-30. doi: 10.1073/pnas.112686799. Epub 2002 Jun 4. Proc Natl Acad Sci U S A. 2002. PMID: 12048239 Free PMC article.
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology.
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, Jucker M. Radde R, et al. Among authors: haass c. EMBO Rep. 2006 Sep;7(9):940-6. doi: 10.1038/sj.embor.7400784. Epub 2006 Aug 11. EMBO Rep. 2006. PMID: 16906128 Free PMC article.
The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system.
Yanagida K, Okochi M, Tagami S, Nakayama T, Kodama TS, Nishitomi K, Jiang J, Mori K, Tatsumi S, Arai T, Ikeuchi T, Kasuga K, Tokuda T, Kondo M, Ikeda M, Deguchi K, Kazui H, Tanaka T, Morihara T, Hashimoto R, Kudo T, Steiner H, Haass C, Tsuchiya K, Akiyama H, Kuwano R, Takeda M. Yanagida K, et al. Among authors: haass c. EMBO Mol Med. 2009 Jul;1(4):223-35. doi: 10.1002/emmm.200900026. EMBO Mol Med. 2009. PMID: 20049724 Free PMC article.
460 results