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Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma cell proliferation.
Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Bouvet M, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: hamada k. Biochem Biophys Rep. 2021 Nov 26;28:101177. doi: 10.1016/j.bbrep.2021.101177. eCollection 2021 Dec. Biochem Biophys Rep. 2021. PMID: 34877414 Free PMC article.
Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells.
Yamamoto J, Han Q, Inubushi S, Sugisawa N, Hamada K, Nishino H, Miyake K, Kumamoto T, Matsuyama R, Bouvet M, Endo I, Hoffman RM. Yamamoto J, et al. Among authors: hamada k. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1034-1038. doi: 10.1016/j.bbrc.2020.09.108. Epub 2020 Oct 3. Biochem Biophys Res Commun. 2020. PMID: 33019978
1,676 results