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Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).
J Med Chem. 2018 Jan 25;61(2):482-491. doi: 10.1021/acs.jmedchem.6b01872. Epub 2017 Apr 17.
J Med Chem. 2018.
PMID: 28379698
HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)*.
Schiedel M, Lehotzky A, Szunyogh S, Oláh J, Hammelmann S, Wössner N, Robaa D, Einsle O, Sippl W, Ovádi J, Jung M.
Schiedel M, et al. Among authors: hammelmann s.
Chembiochem. 2020 Dec 1;21(23):3371-3376. doi: 10.1002/cbic.202000351. Epub 2020 Aug 27.
Chembiochem. 2020.
PMID: 32672888
Free PMC article.
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Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration.
Vogelmann A, Schiedel M, Wössner N, Merz A, Herp D, Hammelmann S, Colcerasa A, Komaniecki G, Hong JY, Sum M, Metzger E, Neuwirt E, Zhang L, Einsle O, Groß O, Schüle R, Lin H, Sippl W, Jung M.
Vogelmann A, et al. Among authors: hammelmann s.
RSC Chem Biol. 2022 Mar 1;3(4):468-485. doi: 10.1039/d1cb00244a. eCollection 2022 Apr 6.
RSC Chem Biol. 2022.
PMID: 35441145
Free PMC article.
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OLN-93 oligodendrocytes synthesize all-trans-retinoic acid in vitro.
Mey J, Hammelmann S.
Mey J, et al. Among authors: hammelmann s.
Cell Tissue Res. 2000 Oct;302(1):49-58. doi: 10.1007/s004410000259.
Cell Tissue Res. 2000.
PMID: 11079715
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