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Hypoxia-induced SETX links replication stress with the unfolded protein response.
Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Ramachandran S, et al. Among authors: hammond em. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. Nat Commun. 2021. PMID: 34140498 Free PMC article.
Hypoxia links ATR and p53 through replication arrest.
Hammond EM, Denko NC, Dorie MJ, Abraham RT, Giaccia AJ. Hammond EM, et al. Mol Cell Biol. 2002 Mar;22(6):1834-43. doi: 10.1128/MCB.22.6.1834-1843.2002. Mol Cell Biol. 2002. PMID: 11865061 Free PMC article.
The role of p53 in hypoxia-induced apoptosis.
Hammond EM, Giaccia AJ. Hammond EM, et al. Biochem Biophys Res Commun. 2005 Jun 10;331(3):718-25. doi: 10.1016/j.bbrc.2005.03.154. Biochem Biophys Res Commun. 2005. PMID: 15865928 Review.
Regulation of autophagy by ATF4 in response to severe hypoxia.
Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL. Rzymski T, et al. Oncogene. 2010 Aug 5;29(31):4424-35. doi: 10.1038/onc.2010.191. Epub 2010 May 31. Oncogene. 2010. PMID: 20514020
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT.
Leszczynska KB, Foskolou IP, Abraham AG, Anbalagan S, Tellier C, Haider S, Span PN, O'Neill EE, Buffa FM, Hammond EM. Leszczynska KB, et al. Among authors: hammond em. J Clin Invest. 2015 Jun;125(6):2385-98. doi: 10.1172/JCI80402. Epub 2015 May 11. J Clin Invest. 2015. PMID: 25961455 Free PMC article.
126 results