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Page 1
P5B-ATPases in the mammalian polyamine transport system and their role in disease.
Azfar M, van Veen S, Houdou M, Hamouda NN, Eggermont J, Vangheluwe P. Azfar M, et al. Among authors: hamouda nn. Biochim Biophys Acta Mol Cell Res. 2022 Dec;1869(12):119354. doi: 10.1016/j.bbamcr.2022.119354. Epub 2022 Sep 2. Biochim Biophys Acta Mol Cell Res. 2022. PMID: 36064065 Free article. Review.
ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress.
Vrijsen S, Besora-Casals L, van Veen S, Zielich J, Van den Haute C, Hamouda NN, Fischer C, Ghesquière B, Tournev I, Agostinis P, Baekelandt V, Eggermont J, Lambie E, Martin S, Vangheluwe P. Vrijsen S, et al. Among authors: hamouda nn. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31198-31207. doi: 10.1073/pnas.1922342117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229544 Free PMC article.
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.
Hamouda NN, Van den Haute C, Vanhoutte R, Sannerud R, Azfar M, Mayer R, Cortés Calabuig Á, Swinnen JV, Agostinis P, Baekelandt V, Annaert W, Impens F, Verhelst SHL, Eggermont J, Martin S, Vangheluwe P. Hamouda NN, et al. J Biol Chem. 2021 Jan-Jun;296:100182. doi: 10.1074/jbc.RA120.013908. Epub 2020 Dec 17. J Biol Chem. 2021. PMID: 33310703 Free PMC article.
Parkinson disease related ATP13A2 evolved early in animal evolution.
Sørensen DM, Holemans T, van Veen S, Martin S, Arslan T, Haagendahl IW, Holen HW, Hamouda NN, Eggermont J, Palmgren M, Vangheluwe P. Sørensen DM, et al. Among authors: hamouda nn. PLoS One. 2018 Mar 5;13(3):e0193228. doi: 10.1371/journal.pone.0193228. eCollection 2018. PLoS One. 2018. PMID: 29505581 Free PMC article.
Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.
Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, Beletchi I, Verstraeten A, Gossye H, Gelders G, Pals P, Hamouda NN, Engelborghs S, Martin JJ, Eggermont J, De Deyn PP, Cras P, Baekelandt V, Vangheluwe P, Van Broeckhoven C; BELNEU consortium. Martin S, et al. Among authors: hamouda nn. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14. Acta Neuropathol. 2020. PMID: 32172343 Free PMC article.