Han S - Search Results

1

Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.

McCorvie TJ, Loria PM, Tu M, Han S, Shrestha L, Froese DS, Ferreira IM, Berg AP, Yue WW. McCorvie TJ, et al. Among authors: han s. Nat Struct Mol Biol. 2022 Jul;29(7):628-638. doi: 10.1038/s41594-022-00799-3. Epub 2022 Jul 14. Nat Struct Mol Biol. 2022. PMID: 35835870 Free PMC article.

2

Expression and functional characterization of human lysosomal acid lipase gene (LIPA) mutation responsible for cholesteryl ester storage disease (CESD) phenotype.

Rajamohan F, Reyes AR, Ruangsiriluk W, Hoth LR, Han S, Caspers N, Tu M, Ward J, Kurumbail RG. Rajamohan F, et al. Among authors: han s. Protein Expr Purif. 2015 Jun;110:22-9. doi: 10.1016/j.pep.2014.12.009. Epub 2015 Jan 22. Protein Expr Purif. 2015. PMID: 25620107

3

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.

Fox NG, Yu X, Feng X, Bailey HJ, Martelli A, Nabhan JF, Strain-Damerell C, Bulawa C, Yue WW, Han S. Fox NG, et al. Among authors: han s. Nat Commun. 2019 May 17;10(1):2210. doi: 10.1038/s41467-019-09989-y. Nat Commun. 2019. PMID: 31101807 Free PMC article.

4

Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease.

Rajamohan F, Reyes AR, Tu M, Nedoma NL, Hoth LR, Schwaid AG, Kurumbail RG, Ward J, Han S. Rajamohan F, et al. Among authors: han s. J Lipid Res. 2020 Aug;61(8):1192-1202. doi: 10.1194/jlr.RA120000748. Epub 2020 Jun 1. J Lipid Res. 2020. PMID: 32482718 Free PMC article.

5

A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.

Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA. Griffith DA, et al. Among authors: han s. J Med Chem. 2022 Jun 23;65(12):8208-8226. doi: 10.1021/acs.jmedchem.1c01856. Epub 2022 Jun 1. J Med Chem. 2022. PMID: 35647711 Free PMC article.

6

Structural basis of the acyl-transfer mechanism of human GPAT1.

Johnson ZL, Ammirati M, Wasilko DJ, Chang JS, Noell S, Foley TL, Yoon H, Smith K, Asano S, Hales K, Wan M, Yang Q, Piotrowski MA, Farley KA, Gilbert T, Aschenbrenner LM, Fennell KF, Dutra JK, Xu M, Guo C, Varghese AE, Bellenger J, Quinn A, Am Ende CW, West GM, Griffor MC, Bennett D, Calabrese M, Steppan CM, Han S, Wu H. Johnson ZL, et al. Among authors: han s. Nat Struct Mol Biol. 2023 Jan;30(1):22-30. doi: 10.1038/s41594-022-00884-7. Epub 2022 Dec 15. Nat Struct Mol Biol. 2023. PMID: 36522428

7

Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Staphyloccocus aureus: structural basis for NaAD interaction in functional dimer.

Han S, Forman MD, Loulakis P, Rosner MH, Xie Z, Wang H, Danley DE, Yuan W, Schafer J, Xu Z. Han S, et al. J Mol Biol. 2006 Jul 21;360(4):814-25. doi: 10.1016/j.jmb.2006.05.055. Epub 2006 Jun 6. J Mol Biol. 2006. PMID: 16784754

8

Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.

Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Hughes TET, et al. Among authors: han x, han s. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323279 Free PMC article.

9

Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20.

Wasilko DJ, Johnson ZL, Ammirati M, Che Y, Griffor MC, Han S, Wu H. Wasilko DJ, et al. Among authors: han s. Nat Commun. 2020 Jun 15;11(1):3031. doi: 10.1038/s41467-020-16820-6. Nat Commun. 2020. PMID: 32541785 Free PMC article.

10

Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics.

Orris B, Huynh KW, Ammirati M, Han S, Bolaños B, Carmody J, Petroski MD, Bosbach B, Shields DJ, Stivers JT. Orris B, et al. Among authors: han s. Nucleic Acids Res. 2022 Jul 22;50(13):7545-7559. doi: 10.1093/nar/gkac573. Nucleic Acids Res. 2022. PMID: 35801923 Free PMC article.

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