Hancock WW - Search Results

1

Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.

Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH. Angelin A, et al. Among authors: hancock ww. Cell Metab. 2017 Jun 6;25(6):1282-1293.e7. doi: 10.1016/j.cmet.2016.12.018. Epub 2017 Apr 13. Cell Metab. 2017. PMID: 28416194 Free PMC article.

2

Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.

Beier UH, Wang L, Bhatti TR, Liu Y, Han R, Ge G, Hancock WW. Beier UH, et al. Among authors: hancock ww. Mol Cell Biol. 2011 Mar;31(5):1022-9. doi: 10.1128/MCB.01206-10. Epub 2011 Jan 3. Mol Cell Biol. 2011. PMID: 21199917 Free PMC article.

3

Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.

Liu Y, Wang L, Han R, Beier UH, Hancock WW. Liu Y, et al. Among authors: hancock ww. PLoS One. 2012;7(1):e29035. doi: 10.1371/journal.pone.0029035. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22247766 Free PMC article.

4

Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms.

Beier UH, Wang L, Han R, Akimova T, Liu Y, Hancock WW. Beier UH, et al. Among authors: hancock ww. Sci Signal. 2012 Jun 19;5(229):ra45. doi: 10.1126/scisignal.2002873. Sci Signal. 2012. PMID: 22715468 Free PMC article.

5

Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity.

Wang L, Liu Y, Beier UH, Han R, Bhatti TR, Akimova T, Hancock WW. Wang L, et al. Among authors: hancock ww. Blood. 2013 May 2;121(18):3631-9. doi: 10.1182/blood-2012-08-451765. Epub 2013 Feb 26. Blood. 2013. PMID: 23444399 Free PMC article.

6

Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.

Liu Y, Wang L, Predina J, Han R, Beier UH, Wang LC, Kapoor V, Bhatti TR, Akimova T, Singhal S, Brindle PK, Cole PA, Albelda SM, Hancock WW. Liu Y, et al. Among authors: hancock ww. Nat Med. 2013 Sep;19(9):1173-7. doi: 10.1038/nm.3286. Epub 2013 Aug 18. Nat Med. 2013. PMID: 23955711 Free PMC article.

7

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

Wang L, Liu Y, Han R, Beier UH, Thomas RM, Wells AD, Hancock WW. Wang L, et al. Among authors: hancock ww. Mol Cell Biol. 2013 Oct;33(20):4106-15. doi: 10.1128/MCB.00144-13. Epub 2013 Aug 26. Mol Cell Biol. 2013. PMID: 23979593 Free PMC article.

8

Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.

Liu Y, Wang L, Han R, Beier UH, Akimova T, Bhatti T, Xiao H, Cole PA, Brindle PK, Hancock WW. Liu Y, et al. Among authors: hancock ww. Mol Cell Biol. 2014 Nov;34(21):3993-4007. doi: 10.1128/MCB.00919-14. Epub 2014 Aug 25. Mol Cell Biol. 2014. PMID: 25154413 Free PMC article.

9

Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.

Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW. Beier UH, et al. Among authors: hancock sa, hancock ww. FASEB J. 2015 Jun;29(6):2315-26. doi: 10.1096/fj.14-268409. Epub 2015 Feb 13. FASEB J. 2015. PMID: 25681462 Free PMC article.

10

Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells.

Jiao J, Han R, Hancock WW, Beier UH. Jiao J, et al. Among authors: hancock ww. Methods Mol Biol. 2017;1510:287-293. doi: 10.1007/978-1-4939-6527-4_21. Methods Mol Biol. 2017. PMID: 27761829 Free PMC article.

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