Handler D - Search Results

1

The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila.

Mohn F, Sienski G, Handler D, Brennecke J. Mohn F, et al. Among authors: handler d. Cell. 2014 Jun 5;157(6):1364-1379. doi: 10.1016/j.cell.2014.04.031. Cell. 2014. PMID: 24906153 Free article.

2

A genome-scale shRNA resource for transgenic RNAi in Drosophila.

Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, Perrimon N. Ni JQ, et al. Among authors: handler d. Nat Methods. 2011 May;8(5):405-7. doi: 10.1038/nmeth.1592. Epub 2011 Apr 3. Nat Methods. 2011. PMID: 21460824 Free PMC article.

3

A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.

Handler D, Olivieri D, Novatchkova M, Gruber FS, Meixner K, Mechtler K, Stark A, Sachidanandam R, Brennecke J. Handler D, et al. EMBO J. 2011 Aug 23;30(19):3977-93. doi: 10.1038/emboj.2011.308. EMBO J. 2011. PMID: 21863019 Free PMC article.

4

The genetic makeup of the Drosophila piRNA pathway.

Handler D, Meixner K, Pizka M, Lauss K, Schmied C, Gruber FS, Brennecke J. Handler D, et al. Mol Cell. 2013 Jun 6;50(5):762-77. doi: 10.1016/j.molcel.2013.04.031. Epub 2013 May 9. Mol Cell. 2013. PMID: 23665231 Free PMC article.

5

The exon junction complex is required for definition and excision of neighboring introns in Drosophila.

Hayashi R, Handler D, Ish-Horowicz D, Brennecke J. Hayashi R, et al. Among authors: handler d. Genes Dev. 2014 Aug 15;28(16):1772-85. doi: 10.1101/gad.245738.114. Epub 2014 Jul 31. Genes Dev. 2014. PMID: 25081352 Free PMC article.

6

Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.

Marinov GK, Wang J, Handler D, Wold BJ, Weng Z, Hannon GJ, Aravin AA, Zamore PD, Brennecke J, Toth KF. Marinov GK, et al. Among authors: handler d. Dev Cell. 2015 Mar 23;32(6):765-71. doi: 10.1016/j.devcel.2015.01.013. Dev Cell. 2015. PMID: 25805138 Free PMC article.

7

Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis.

Mohn F, Handler D, Brennecke J. Mohn F, et al. Among authors: handler d. Science. 2015 May 15;348(6236):812-817. doi: 10.1126/science.aaa1039. Science. 2015. PMID: 25977553 Free PMC article.

8

Genetic and mechanistic diversity of piRNA 3'-end formation.

Hayashi R, Schnabl J, Handler D, Mohn F, Ameres SL, Brennecke J. Hayashi R, et al. Among authors: handler d. Nature. 2016 Nov 24;539(7630):588-592. doi: 10.1038/nature20162. Epub 2016 Nov 16. Nature. 2016. PMID: 27851737 Free PMC article.

9

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.

Batki J, Schnabl J, Wang J, Handler D, Andreev VI, Stieger CE, Novatchkova M, Lampersberger L, Kauneckaite K, Xie W, Mechtler K, Patel DJ, Brennecke J. Batki J, et al. Among authors: handler d. Nat Struct Mol Biol. 2019 Aug;26(8):720-731. doi: 10.1038/s41594-019-0270-6. Epub 2019 Aug 5. Nat Struct Mol Biol. 2019. PMID: 31384064 Free PMC article.

10

A universal method for the rapid isolation of all known classes of functional silencing small RNAs.

Grentzinger T, Oberlin S, Schott G, Handler D, Svozil J, Barragan-Borrero V, Humbert A, Duharcourt S, Brennecke J, Voinnet O. Grentzinger T, et al. Among authors: handler d. Nucleic Acids Res. 2020 Aug 20;48(14):e79. doi: 10.1093/nar/gkaa472. Nucleic Acids Res. 2020. PMID: 32496553 Free PMC article.

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