Handschuh S - Search Results

1

Design, synthesis, and evaluation of indolinones as triple angiokinase inhibitors and the discovery of a highly specific 6-methoxycarbonyl-substituted indolinone (BIBF 1120).

Roth GJ, Heckel A, Colbatzky F, Handschuh S, Kley J, Lehmann-Lintz T, Lotz R, Tontsch-Grunt U, Walter R, Hilberg F. Roth GJ, et al. Among authors: handschuh s. J Med Chem. 2009 Jul 23;52(14):4466-80. doi: 10.1021/jm900431g. J Med Chem. 2009. PMID: 19522465

2

Heterocyclic thrombin inhibitors. Part 2: quinoxalinone derivatives as novel, potent antithrombotic agents.

Ries UJ, Priepke HW, Hauel NH, Handschuh S, Mihm G, Stassen JM, Wienen W, Nar H. Ries UJ, et al. Among authors: handschuh s. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2297-302. doi: 10.1016/s0960-894x(03)00443-8. Bioorg Med Chem Lett. 2003. PMID: 12824021

3

Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.

Kuttruff CA, Ferrara M, Bretschneider T, Hoerer S, Handschuh S, Nosse B, Romig H, Nicklin P, Roth GJ. Kuttruff CA, et al. Among authors: handschuh s. ACS Med Chem Lett. 2017 Nov 8;8(12):1252-1257. doi: 10.1021/acsmedchemlett.7b00312. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259743 Free PMC article.

4

A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state.

Schnapp G, Neubauer H, Büttner FH, Handschuh S, Lingard I, Heilker R, Klinder K, Prestle J, Walter R, Wolff M, Zeeb M, Debaene F, Nar H, Fiegen D. Schnapp G, et al. Among authors: handschuh s. Commun Chem. 2020 Jun 10;3(1):75. doi: 10.1038/s42004-020-0321-2. Commun Chem. 2020. PMID: 36703453 Free PMC article.

5

Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer.

Kuttruff CA, Fleck M, Carotta S, Arnhof H, Bretschneider T, Dahmann G, Gremel G, Grube A, Handschuh S, Heimann A, Hofmann MH, Impagnatiello MA, Nar H, Rast G, Schaaf O, Schmidt E, Oost T. Kuttruff CA, et al. Among authors: handschuh s. J Med Chem. 2023 Jul 27;66(14):9376-9400. doi: 10.1021/acs.jmedchem.3c00510. Epub 2023 Jul 14. J Med Chem. 2023. PMID: 37450324

6

Stabilizing of a globular protein by a highly complex water network: a molecular dynamics simulation study on factor Xa.

Wallnoefer HG, Handschuh S, Liedl KR, Fox T. Wallnoefer HG, et al. Among authors: handschuh s. J Phys Chem B. 2010 Jun 3;114(21):7405-12. doi: 10.1021/jp101654g. J Phys Chem B. 2010. PMID: 20446703

7

Theoretical prediction of hydrogen bond strength for use in molecular modeling.

Nocker M, Handschuh S, Tautermann C, Liedl KR. Nocker M, et al. Among authors: handschuh s. J Chem Inf Model. 2009 Sep;49(9):2067-76. doi: 10.1021/ci9001469. J Chem Inf Model. 2009. PMID: 19715345

8

Nuttalliellidae in Burmese amber: implications for tick evolution.

Chitimia-Dobler L, Handschuh S, Dunlop JA, Pienaar R, Mans BJ. Chitimia-Dobler L, et al. Among authors: handschuh s. Parasitology. 2024 Apr 16:1-17. doi: 10.1017/S0031182024000477. Online ahead of print. Parasitology. 2024. PMID: 38623697

9

Comparative diagnostic imaging in giant African land snails (Achatinidae).

Gumpenberger M, Schmidt-Ukaj S, Handschuh S. Gumpenberger M, et al. Among authors: handschuh s. Front Vet Sci. 2023 Oct 3;10:1223784. doi: 10.3389/fvets.2023.1223784. eCollection 2023. Front Vet Sci. 2023. PMID: 37854094 Free PMC article.

10

High-Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies Using Intact Mass Spectrometry.

Ziegengeist T, Orth J, Kroll K, Schneider M, Spindler N, Dimova D, Handschuh S, Brandenburg A, Ossola R, Furtmann N, Birkenfeld J, Beil C, Hoffmann D, Schmidt T, Sendak R, Fischer M, Hölper S, Kühn J. Ziegengeist T, et al. Among authors: handschuh s. Anal Chem. 2023 Jul 11;95(27):10265-10278. doi: 10.1021/acs.analchem.3c00742. Epub 2023 Jun 27. Anal Chem. 2023. PMID: 37369001

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