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Did you mean hans vellema[Author] (1 results)?
VHL-deficiency leads to reductive stress in renal cells.
Vellama H, Eskla KL, Eichelmann H, Hüva A, Tennant DA, Thakker A, Roberts J, Jagomäe T, Porosk R, Laisk A, Oja V, Rämma H, Volke V, Vasar E, Luuk H. Vellama H, et al. Free Radic Biol Med. 2023 Nov 1;208:1-12. doi: 10.1016/j.freeradbiomed.2023.07.029. Epub 2023 Jul 26. Free Radic Biol Med. 2023. PMID: 37506952 Free PMC article.
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
Westbrook RL, Bridges E, Roberts J, Escribano-Gonzalez C, Eales KL, Vettore LA, Walker PD, Vera-Siguenza E, Rana H, Cuozzo F, Eskla KL, Vellama H, Shaaban A, Nixon C, Luuk H, Lavery GG, Hodson DJ, Harris AL, Tennant DA. Westbrook RL, et al. Among authors: vellama h. Cell Rep. 2022 Feb 1;38(5):110320. doi: 10.1016/j.celrep.2022.110320. Cell Rep. 2022. PMID: 35108535 Free PMC article.