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DNA-binding mechanism and evolution of replication protein A.
Madru C, Martínez-Carranza M, Laurent S, Alberti AC, Chevreuil M, Raynal B, Haouz A, Le Meur RA, Delarue M, Henneke G, Flament D, Krupovic M, Legrand P, Sauguet L. Madru C, et al. Among authors: haouz a. Nat Commun. 2023 Apr 22;14(1):2326. doi: 10.1038/s41467-023-38048-w. Nat Commun. 2023. PMID: 37087464 Free PMC article.
Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site.
Topalis D, Kumamoto H, Amaya Velasco MF, Dugué L, Haouz A, Alexandre JAC, Gallois-Montbrun S, Alzari PM, Pochet S, Agrofoglio LA, Deville-Bonne D. Topalis D, et al. Among authors: haouz a. FEBS J. 2007 Jul;274(14):3704-3714. doi: 10.1111/j.1742-4658.2007.05902.x. Epub 2007 Jul 2. FEBS J. 2007. PMID: 17608725 Free article.
First-in-class allosteric inhibitors of bacterial IMPDHs.
Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugué L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H. Alexandre T, et al. Among authors: haouz a. Eur J Med Chem. 2019 Apr 1;167:124-132. doi: 10.1016/j.ejmech.2019.01.064. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30769241 Free article.
112 results