Hardelin JP - Search Results

1

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.

Lefèvre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C. Lefèvre G, et al. Among authors: hardelin jp. Development. 2008 Apr;135(8):1427-37. doi: 10.1242/dev.012922. Epub 2008 Mar 13. Development. 2008. PMID: 18339676

2

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

Michalski N, Michel V, Bahloul A, Lefèvre G, Barral J, Yagi H, Chardenoux S, Weil D, Martin P, Hardelin JP, Sato M, Petit C. Michalski N, et al. Among authors: hardelin jp. J Neurosci. 2007 Jun 13;27(24):6478-88. doi: 10.1523/JNEUROSCI.0342-07.2007. J Neurosci. 2007. PMID: 17567809 Free PMC article.

3

Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells.

Michalski N, Michel V, Caberlotto E, Lefèvre GM, van Aken AF, Tinevez JY, Bizard E, Houbron C, Weil D, Hardelin JP, Richardson GP, Kros CJ, Martin P, Petit C. Michalski N, et al. Among authors: hardelin jp. Pflugers Arch. 2009 Nov;459(1):115-30. doi: 10.1007/s00424-009-0711-x. Pflugers Arch. 2009. PMID: 19756723 Free PMC article.

4

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.

Etournay R, Lepelletier L, Boutet de Monvel J, Michel V, Cayet N, Leibovici M, Weil D, Foucher I, Hardelin JP, Petit C. Etournay R, et al. Among authors: hardelin jp. Development. 2010 Apr;137(8):1373-83. doi: 10.1242/dev.045138. Development. 2010. PMID: 20332152

5

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

Delprat B, Michel V, Goodyear R, Yamasaki Y, Michalski N, El-Amraoui A, Perfettini I, Legrain P, Richardson G, Hardelin JP, Petit C. Delprat B, et al. Among authors: hardelin jp. Hum Mol Genet. 2005 Feb 1;14(3):401-10. doi: 10.1093/hmg/ddi036. Epub 2004 Dec 8. Hum Mol Genet. 2005. PMID: 15590698

6

[Usher syndrome type I and the differentiation of inner ear sensory cells' hair bundles].

El-Amraoui A, Lefèvre G, Hardelin JP, Petit C. El-Amraoui A, et al. Among authors: hardelin jp. Med Sci (Paris). 2005 Aug-Sep;21(8-9):737-40. doi: 10.1051/medsci/2005218-9737. Med Sci (Paris). 2005. PMID: 16115459 Free article. Review. French.

7

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

Verpy E, Weil D, Leibovici M, Goodyear RJ, Hamard G, Houdon C, Lefèvre GM, Hardelin JP, Richardson GP, Avan P, Petit C. Verpy E, et al. Among authors: hardelin jp. Nature. 2008 Nov 13;456(7219):255-8. doi: 10.1038/nature07380. Epub 2008 Oct 8. Nature. 2008. PMID: 18849963 Free PMC article.

8

Vezatin, an integral membrane protein of adherens junctions, is required for the sound resilience of cochlear hair cells.

Bahloul A, Simmler MC, Michel V, Leibovici M, Perfettini I, Roux I, Weil D, Nouaille S, Zuo J, Zadro C, Licastro D, Gasparini P, Avan P, Hardelin JP, Petit C. Bahloul A, et al. Among authors: hardelin jp. EMBO Mol Med. 2009 May;1(2):125-38. doi: 10.1002/emmm.200900015. EMBO Mol Med. 2009. PMID: 20049712 Free PMC article.

9

Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids.

Bahloul A, Michel V, Hardelin JP, Nouaille S, Hoos S, Houdusse A, England P, Petit C. Bahloul A, et al. Among authors: hardelin jp. Hum Mol Genet. 2010 Sep 15;19(18):3557-65. doi: 10.1093/hmg/ddq271. Epub 2010 Jul 16. Hum Mol Genet. 2010. PMID: 20639393 Free PMC article.

10

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.

Caberlotto E, Michel V, Foucher I, Bahloul A, Goodyear RJ, Pepermans E, Michalski N, Perfettini I, Alegria-Prévot O, Chardenoux S, Do Cruzeiro M, Hardelin JP, Richardson GP, Avan P, Weil D, Petit C. Caberlotto E, et al. Among authors: hardelin jp. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30. doi: 10.1073/pnas.1017114108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21436032 Free PMC article.

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