Harding SM - Search Results

1

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG. Al Rashid ST, et al. Among authors: harding sm. Radiat Res. 2011 May;175(5):588-98. doi: 10.1667/RR2084.1. Epub 2011 Mar 1. Radiat Res. 2011. PMID: 21361779

2

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer.

Li L, Halaby MJ, Hakem A, Cardoso R, El Ghamrasni S, Harding S, Chan N, Bristow R, Sanchez O, Durocher D, Hakem R. Li L, et al. J Exp Med. 2010 May 10;207(5):983-97. doi: 10.1084/jem.20092437. Epub 2010 Apr 12. J Exp Med. 2010. PMID: 20385750 Free PMC article.

3

Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.

Sanli T, Rashid A, Liu C, Harding S, Bristow RG, Cutz JC, Singh G, Wright J, Tsakiridis T. Sanli T, et al. Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):221-9. doi: 10.1016/j.ijrobp.2010.03.005. Epub 2010 Jul 7. Int J Radiat Oncol Biol Phys. 2010. PMID: 20615625

4

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.

O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, Mendez M, Mullin M, Sun T, Habermann B, Datti A, Bristow RG, Gingras AC, Tyers MD, Brown GW, Durocher D. O'Donnell L, et al. Among authors: harding sm. Mol Cell. 2010 Nov 24;40(4):619-31. doi: 10.1016/j.molcel.2010.10.024. Epub 2010 Nov 4. Mol Cell. 2010. PMID: 21055983 Free PMC article.

5

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG. Fraser M, et al. Among authors: harding sm. Cell Cycle. 2011 Jul 1;10(13):2218-32. doi: 10.4161/cc.10.13.16305. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21623170

6

ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells.

Harding SM, Coackley C, Bristow RG. Harding SM, et al. Radiother Oncol. 2011 Jun;99(3):307-12. doi: 10.1016/j.radonc.2011.05.039. Epub 2011 Jun 15. Radiother Oncol. 2011. PMID: 21680038

7

A role for p53 in the response of bystander cells to receipt of medium borne signals from irradiated cells.

Mothersill C, Bristow RG, Harding SM, Smith RW, Mersov A, Seymour CB. Mothersill C, et al. Among authors: harding sm. Int J Radiat Biol. 2011 Nov;87(11):1120-5. doi: 10.3109/09553002.2011.610866. Int J Radiat Biol. 2011. PMID: 21831006

8

Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks.

Harding SM, Bristow RG. Harding SM, et al. Cell Cycle. 2012 Apr 1;11(7):1432-44. doi: 10.4161/cc.19824. Epub 2012 Apr 1. Cell Cycle. 2012. PMID: 22421153

9

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.

Shibata A, Moiani D, Arvai AS, Perry J, Harding SM, Genois MM, Maity R, van Rossum-Fikkert S, Kertokalio A, Romoli F, Ismail A, Ismalaj E, Petricci E, Neale MJ, Bristow RG, Masson JY, Wyman C, Jeggo PA, Tainer JA. Shibata A, et al. Among authors: harding sm. Mol Cell. 2014 Jan 9;53(1):7-18. doi: 10.1016/j.molcel.2013.11.003. Epub 2013 Dec 5. Mol Cell. 2014. PMID: 24316220 Free PMC article.

10

Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.

El Ghamrasni S, Cardoso R, Halaby MJ, Zeegers D, Harding S, Kumareswaran R, Yavorska T, Chami N, Jurisicova A, Sanchez O, Hande MP, Bristow R, Hakem R, Hakem A. El Ghamrasni S, et al. Oncogene. 2015 Apr 2;34(14):1780-9. doi: 10.1038/onc.2014.121. Epub 2014 May 26. Oncogene. 2015. PMID: 24858046

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