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Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis.
Reske JJ, Wilson MR, Holladay J, Siwicki RA, Skalski H, Harkins S, Adams M, Risinger JI, Hostetter G, Lin K, Chandler RL. Reske JJ, et al. Among authors: harkins s. PLoS Genet. 2021 Dec 23;17(12):e1009986. doi: 10.1371/journal.pgen.1009986. eCollection 2021 Dec. PLoS Genet. 2021. PMID: 34941867 Free PMC article.
Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling.
Schreiber C, Saraswati S, Harkins S, Gruber A, Cremers N, Thiele W, Rothley M, Plaumann D, Korn C, Armant O, Augustin HG, Sleeman JP. Schreiber C, et al. Among authors: harkins s. PLoS Genet. 2019 Jun 27;15(6):e1008216. doi: 10.1371/journal.pgen.1008216. eCollection 2019 Jun. PLoS Genet. 2019. PMID: 31246957 Free PMC article.
Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis.
Schreiber C, Gruber A, Roßwag S, Saraswati S, Harkins S, Thiele W, Foroushani ZH, Munding N, Schmaus A, Rothley M, Dimmler A, Tanaka M, Garvalov BK, Sleeman JP. Schreiber C, et al. Among authors: harkins s. Cancer Lett. 2022 May 1;533:215600. doi: 10.1016/j.canlet.2022.215600. Epub 2022 Feb 15. Cancer Lett. 2022. PMID: 35181478
Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features.
Zhou XA, Yang J, Ringbloom KG, Martinez-Escala ME, Stevenson KE, Wenzel AT, Fantini D, Martin HK, Moy AP, Morgan EA, Harkins S, Paxton CN, Hong B, Andersen EF, Guitart J, Weinstock DM, Cerroni L, Choi J, Louissaint A. Zhou XA, et al. Among authors: harkins s. Blood Adv. 2021 Feb 9;5(3):649-661. doi: 10.1182/bloodadvances.2020002469. Blood Adv. 2021. PMID: 33560380 Free PMC article.
Pan-Cancer Landscape Analysis Reveals Recurrent KMT2A-MAML2 Gene Fusion in Aggressive Histologic Subtypes of Thymoma.
Massoth LR, Hung YP, Dias-Santagata D, Onozato M, Shah N, Severson E, Duncan D, Gillespie BJ, Williams NF, Ross JS, Vergilio JA, Harkins SK, Glomski K, Nardi V, Zukerberg LR, Hasserjian RP, Louissaint A Jr, Williams EA. Massoth LR, et al. Among authors: harkins sk. JCO Precis Oncol. 2020 Feb 26;4:PO.19.00288. doi: 10.1200/PO.19.00288. eCollection 2020. JCO Precis Oncol. 2020. PMID: 32923872 Free PMC article.
Next-generation ALK inhibitors are highly active in ALK-positive large B-cell lymphoma.
Soumerai JD, Rosenthal A, Harkins S, Duffy J, Mecca C, Wang Y, Grewal RK, El-Jawahri AR, Liu H, Menard C, Dogan A, Yang L, Rimsza LM, Bantilan K, Martin H, Lei M, Mohr S, Kurilovich A, Kudryashova O, Postovalova E, Nardi V, Abramson JS, Chiarle R, Zelenetz AD, Louissaint A Jr. Soumerai JD, et al. Among authors: harkins s. Blood. 2022 Oct 20;140(16):1822-1826. doi: 10.1182/blood.2022015443. Blood. 2022. PMID: 35802834 Free PMC article. No abstract available.
Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation.
Olmedillas E, Rajamanickam RR, Avalos RD, Sosa FA, Zandonatti MA, Harkins SS, Shresta S, Hastie KM, Saphire EO. Olmedillas E, et al. Among authors: harkins ss. bioRxiv [Preprint]. 2023 Dec 15:2023.12.14.571764. doi: 10.1101/2023.12.14.571764. bioRxiv. 2023. PMID: 38168261 Free PMC article. Preprint.
162 results