Harrison T - Search Results

1

Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus.

Maubach KA, Martin K, Chicchi G, Harrison T, Wheeldon A, Swain CJ, Cumberbatch MJ, Rupniak NM, Seabrook GR. Maubach KA, et al. Among authors: harrison t. Neuroscience. 2002;109(3):609-17. doi: 10.1016/s0306-4522(01)00467-5. Neuroscience. 2002. PMID: 11823070

2

Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity.

Conley RK, Cumberbatch MJ, Mason GS, Williamson DJ, Harrison T, Locker K, Swain C, Maubach K, O'Donnell R, Rigby M, Hewson L, Smith D, Rupniak NM. Conley RK, et al. Among authors: harrison t. J Neurosci. 2002 Sep 1;22(17):7730-6. doi: 10.1523/JNEUROSCI.22-17-07730.2002. J Neurosci. 2002. PMID: 12196596 Free PMC article.

3

Substance P stimulates inhibitory synaptic transmission in the guinea pig basolateral amygdala in vitro.

Maubach KA, Martin K, Smith DW, Hewson L, Frankshun RA, Harrison T, Seabrook GR. Maubach KA, et al. Among authors: harrison t. Neuropharmacology. 2001 May;40(6):806-17. doi: 10.1016/s0028-3908(00)00209-4. Neuropharmacology. 2001. PMID: 11369034

4

Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1 ) receptor in assays for antidepressant and anxiolytic drugs.

Rupniak NM, Carlson EJ, Webb JK, Harrison T, Porsolt RD, Roux S, de Felipe C, Hunt SP, Oates B, Wheeldon A. Rupniak NM, et al. Among authors: harrison t. Behav Pharmacol. 2001 Nov;12(6-7):497-508. doi: 10.1097/00008877-200111000-00011. Behav Pharmacol. 2001. PMID: 11742144

5

Spirocyclic NK(1) antagonists II: [4.5]-spiroethers.

Williams BJ, Cascieri MA, Chicchi GG, Harrison T, Owens AP, Owen SN, Rupniak NM, Tattersall DF, Williams A, Swain CJ. Williams BJ, et al. Among authors: harrison t. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2719-22. doi: 10.1016/s0960-894x(02)00509-7. Bioorg Med Chem Lett. 2002. PMID: 12217362

6

L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2+]i mobilisation, cardiovascular and dural extravasation assays.

Seabrook GR, Shepheard SL, Williamson DJ, Tyrer P, Rigby M, Cascieri MA, Harrison T, Hargreaves RJ, Hill RG. Seabrook GR, et al. Among authors: harrison t. Eur J Pharmacol. 1996 Dec 12;317(1):129-35. doi: 10.1016/s0014-2999(96)00706-6. Eur J Pharmacol. 1996. PMID: 8982729

7

Distinct mechanism for antidepressant activity by blockade of central substance P receptors.

Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, Reines SA, Liu G, Snavely D, Wyatt-Knowles E, Hale JJ, Mills SG, MacCoss M, Swain CJ, Harrison T, Hill RG, Hefti F, Scolnick EM, Cascieri MA, Chicchi GG, Sadowski S, Williams AR, Hewson L, Smith D, Carlson EJ, Hargreaves RJ, Rupniak NM. Kramer MS, et al. Among authors: harrison t. Science. 1998 Sep 11;281(5383):1640-5. doi: 10.1126/science.281.5383.1640. Science. 1998. PMID: 9733503 Clinical Trial.

8

4,4-Disubstituted piperidine high-affinity NK1 antagonists: structure-activity relationships and in vivo activity.

Stevenson GI, Huscroft I, MacLeod AM, Swain CJ, Cascieri MA, Chicchi GG, Graham MI, Harrison T, Kelleher FJ, Kurtz M, Ladduwahetty T, Merchant KJ, Metzger JM, MacIntyre DE, Sadowski S, Sohal B, Owens AP. Stevenson GI, et al. Among authors: harrison t. J Med Chem. 1998 Nov 5;41(23):4623-35. doi: 10.1021/jm980376b. J Med Chem. 1998. PMID: 9804702

9

High affinity phenylglycinol-based NK1 receptor antagonists.

Owens AP, Harrison T, Moseley JD, Swain CJ, Sadowski S, Cascieri MA. Owens AP, et al. Among authors: harrison t. Bioorg Med Chem Lett. 1998 Jan 6;8(1):51-6. doi: 10.1016/s0960-894x(97)10163-9. Bioorg Med Chem Lett. 1998. PMID: 9871627

10

High affinity, selective neurokinin 2 and neurokinin 3 receptor antagonists from a common structural template.

Harrison T, Korsgaard MP, Swain CJ, Cascieri MA, Sadowski S, Seabrook GR. Harrison T, et al. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1343-8. doi: 10.1016/s0960-894x(98)00215-7. Bioorg Med Chem Lett. 1998. PMID: 9871763

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

2,258 results

Search Page