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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1964 1
1965 2
1966 1
1967 1
1981 1
1989 1
2002 4
2003 4
2004 3
2005 2
2006 1
2007 2
2008 1
2009 3
2010 2
2011 9
2012 5
2013 6
2014 5
2015 4
2016 2
2017 4
2018 8
2019 8
2020 9
2021 7
2022 6
2023 1
2024 1

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97 results

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Page 1
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: hartley rc. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord ENJ, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, Rogatti S, Hartley RC, Eaton S, Costa ASH, Brookes PS, Davidson SM, Duchen MR, Saeb-Parsy K, Shattock MJ, Robinson AJ, Work LM, Frezza C, Krieg T, Murphy MP. Chouchani ET, et al. Among authors: hartley rc. Nature. 2014 Nov 20;515(7527):431-435. doi: 10.1038/nature13909. Epub 2014 Nov 5. Nature. 2014. PMID: 25383517 Free PMC article.
Mitochondrial pharmacology.
Smith RA, Hartley RC, Cochemé HM, Murphy MP. Smith RA, et al. Among authors: hartley rc. Trends Pharmacol Sci. 2012 Jun;33(6):341-52. doi: 10.1016/j.tips.2012.03.010. Epub 2012 Apr 18. Trends Pharmacol Sci. 2012. PMID: 22521106 Free article. Review.
Mitochondria as a therapeutic target for common pathologies.
Murphy MP, Hartley RC. Murphy MP, et al. Among authors: hartley rc. Nat Rev Drug Discov. 2018 Dec;17(12):865-886. doi: 10.1038/nrd.2018.174. Epub 2018 Nov 5. Nat Rev Drug Discov. 2018. PMID: 30393373 Review.
Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.
Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT. Ryan DG, et al. Among authors: hartley rc. iScience. 2022 Jan 30;25(2):103827. doi: 10.1016/j.isci.2022.103827. eCollection 2022 Feb 18. iScience. 2022. PMID: 35198887 Free PMC article.
Mitochondria-targeted small molecule therapeutics and probes.
Smith RA, Hartley RC, Murphy MP. Smith RA, et al. Among authors: hartley rc. Antioxid Redox Signal. 2011 Dec 15;15(12):3021-38. doi: 10.1089/ars.2011.3969. Epub 2011 Jun 6. Antioxid Redox Signal. 2011. PMID: 21395490 Review.
Tetra-arylborate lipophilic anions as targeting groups.
Gaddale Devanna KK , Gawel JM , Prime TA , Cvetko F , Benincá C , Caldwell ST , Negoda A , Harrison A , James AM , Pavlov EV , Murphy MP , Hartley RC . Gaddale Devanna KK , et al. Among authors: hartley rc. Chem Commun (Camb). 2021 Mar 28;57(25):3147-3150. doi: 10.1039/d0cc07924c. Epub 2021 Feb 26. Chem Commun (Camb). 2021. PMID: 33634803 Free PMC article.
MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Shchepinova MM, Cairns AG, Prime TA, Logan A, James AM, Hall AR, Vidoni S, Arndt S, Caldwell ST, Prag HA, Pell VR, Krieg T, Mulvey JF, Yadav P, Cobley JN, Bright TP, Senn HM, Anderson RF, Murphy MP, Hartley RC. Shchepinova MM, et al. Among authors: hartley rc. Cell Chem Biol. 2017 Oct 19;24(10):1285-1298.e12. doi: 10.1016/j.chembiol.2017.08.003. Epub 2017 Sep 7. Cell Chem Biol. 2017. PMID: 28890317 Free PMC article.
Using exomarkers to assess mitochondrial reactive species in vivo.
Logan A, Cochemé HM, Li Pun PB, Apostolova N, Smith RA, Larsen L, Larsen DS, James AM, Fearnley IM, Rogatti S, Prime TA, Finichiu PG, Dare A, Chouchani ET, Pell VR, Methner C, Quin C, McQuaker SJ, Krieg T, Hartley RC, Murphy MP. Logan A, et al. Among authors: hartley rc. Biochim Biophys Acta. 2014 Feb;1840(2):923-30. doi: 10.1016/j.bbagen.2013.05.026. Epub 2013 May 30. Biochim Biophys Acta. 2014. PMID: 23726990 Free article. Review.
Photoactivated release of membrane impermeant sulfonates inside cells.
Caldwell ST, O'Byrne SN, Wilson C, Cvetko F, Murphy MP, McCarron JG, Hartley RC. Caldwell ST, et al. Among authors: hartley rc. Chem Commun (Camb). 2021 Apr 25;57(32):3917-3920. doi: 10.1039/d0cc07713e. Epub 2021 Mar 23. Chem Commun (Camb). 2021. PMID: 33871501 Free PMC article.
97 results